RecruitingNot ApplicableNCT04334031

Deployment o the Multidisciplinary Prospective Cohort Imminent


Sponsor

University Hospital, Lille

Enrollment

2,200 participants

Start Date

Jul 20, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

Immune-mediated inflammatory diseases (IMIDs) most often affect young patients and have high impact on morbidity and mortality with a significant alteration in the quality of life of patients with professional, social and emotional repercussions. Beyond this burden, IMIDs share many common pathophysiological mechanisms and treatments, known as "targeted therapies". Despite progress in this field, much remains to be done in clinical, therapeutic and fundamental research to address the efficacy, resistance and side-effects of treatment. These similarities between IMIDs have led the FHU IMMINeNT to propose the creation of a prospective, multidisciplinary clinical-biological database (IMMINeNT cohort), associated to a biobank, of patients with IMIDs. The main objectives of this database will be to identify new prognostic and therapeutic biomarkers in order to develop new therapeutic targets and biomarkers, to identify prognostic factors and determinants related to the activity, severity and quality of life of patients with IMIDs as well as to the response and tolerance to treatment.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is building a database to study patients with immune-related inflammatory diseases (such as inflammatory arthritis, skin conditions, or neurological diseases) over time. You may be eligible if... - You are a patient at the Lille University Hospital being treated for an immune-mediated inflammatory disease in certain departments (dermatology, internal medicine, neurology, lung medicine, or rheumatology) - You have health insurance coverage - You can understand the study and provide written consent You may NOT be eligible if... - You are unable to participate in the full study or give informed consent - You are pregnant or breastfeeding - You are under legal protection, a minor, or in an emergency situation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

GENETICBiobanking with genetic analysis

Patients included in the IMMINeNT cohort will be collected 7 blood samples for the research project at each revaluation visit. For patients who accepted, genetic analysis (DNA analysis) will be done on a part of those samples.

OTHERSF-12 questionnaire

Patients included in the IMMINeNT cohort will be asked to complete SF-12 quality of life questionnaire.


Locations(1)

Hop Claude Huriez Chu Lille

Lille, France

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NCT04334031


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