RecruitingNCT04439708
Biomarkers and Choroidal Neovascularization
Biomarkers Analysis of Mineralocortoid Receptor Activation in the Serum and Ocular Fluid of Patients With Choroidal Neovascularization
Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Enrollment
250 participants
Start Date
Jul 6, 2020
Study Type
OBSERVATIONAL
Conditions
Summary
The aim of the study is to find biomarkers in the blood and aqueous humor of patients with type 1 choroidal neovascularization and correlate them with the response to anti-VEGF treatment.
Eligibility
Min Age: 18 YearsMax Age: 90 Years
Inclusion Criteria8
- Patients of group 1:
- Patients with type 1 choroidal neovascularization in a context of central serous chorioretinoathy or age related macular degeneration
- Patients without intravitreal injection or last intravitreal injection > 3 months
- Informed signed consent
- Patients of group 2:
- Patients without choroidal neovascularization
- Patients with intraocular surgery (cataract or vitrectomy surgery)
- Signed consent
Exclusion Criteria8
- Myocardial infarction < 12 months
- Chronic renal failure
- Inflammatory disease
- Infectious disease :HIV, viral hepatitis, tuberculosis
- Type 1 or 2 Diabetes
- Patients treated by mineralocorticoid antagonist treatment.
- Type 2 or 3 choroidal neovascularization
- Pregnant woman
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
OTHERBlood and aqueous humor biomarker of treatment response
Blood analyses and aqueous humor analysis
Locations(2)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04439708
Related Trials
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
NCT0744022587 locations
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
NCT0749656756 locations
Effect of Video Viewing on Intravitreal Injection Experience
NCT070023721 location
Dynamic Hormone Profiling and Multimodal Data Capture in Primary Aldosteronism
NCT064959831 location