RecruitingNCT04496687

International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry

The International Spontaneous Coronary Artery Dissection "iSCAD" Registry (SCAD)


Sponsor

SCAD Alliance

Enrollment

1,000 participants

Start Date

Mar 8, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of "iSCAD," the International Spontaneous Coronary Artery Dissection (SCAD) Registry, is to serve as an internationally collaborative, multicenter registry coordinated by an experienced and centralized coordinating center in an effort to increase the pace of participant recruitment, and thereby increase statistical power of studies related to SCAD. The ultimate goal of iSCAD Registry is to facilitate the development of best practices and clinical guidelines for preventing SCAD or its recurrence. This observational study will be prospective and retrospective in its recruitment and will collect clinical information to better understand the natural history and prognosis for SCAD.


Eligibility

Min Age: 18 Years

Inclusion Criteria7

  • Participants with a new diagnosis of SCAD or a history of confirmed or suspected SCAD will be prospectively recruited from either:
  • Inpatient wards of the enrolling medical centers during the acute presentation of SCAD, or
  • Outpatient cardiovascular clinics of enrolling medical centers.
  • Participants must be:
  • years of age or older
  • Diagnosis of SCAD or history of SCAD based on coronary angiography, either catheter-based or coronary CTA
  • Suspected SCAD by coronary angiography

Exclusion Criteria4

  • Coronary dissection in association with atherosclerosis or as a result of iatrogenic injury
  • Inability to provide informed consent
  • Inability to complete study-related patient questionnaires
  • Inability to understand and complete patient questionnaires independently

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Locations(31)

Cedars Sinai

Los Angeles, California, United States

UCLA (University of California, Los Angeles)

Los Angeles, California, United States

Kaiser Permanente Northern California

San Francisco, California, United States

University of Colorado

Aurora, Colorado, United States

Hartford Hospital

Hartford, Connecticut, United States

University of South Florida

Tampa, Florida, United States

Emory Healthcare System

Atlanta, Georgia, United States

Northwestern Medicine

Chicago, Illinois, United States

University of Kentucky

Lexington, Kentucky, United States

Johns Hopkins

Baltimore, Maryland, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

St. Luke's Mid America

Kansas City, Missouri, United States

Washington University

St Louis, Missouri, United States

Dartmouth-Hitchcock

Lebanon, New Hampshire, United States

Catholic Medical Center

Manchester, New Hampshire, United States

Mount Sinai

New York, New York, United States

Columbia University Medical Center

New York, New York, United States

Atrium Health Sanger Heart and Vascular Institute

Charlotte, North Carolina, United States

University Hospitals--Case Western

Cleveland, Ohio, United States

Oklahoma Heart

Oklahoma City, Oklahoma, United States

Providence

Portland, Oregon, United States

University of Pennsylvania

Philadelphia, Pennsylvania, United States

Allegheny General Hospital, Allegheny Health Network

Pittsburgh, Pennsylvania, United States

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States

Vanderbilt University Medical Center

Nashville, Tennessee, United States

UT Southwestern

Dallas, Texas, United States

Intermountain

Murray, Utah, United States

University of Virginia

Charlottesville, Virginia, United States

Inova Heart & Vascular Institute

Fairfax, Virginia, United States

University of Washington Medicine

Seattle, Washington, United States

Victor Chang Cardiac Research Institute

Darlinghurst, New South Wales, Australia

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NCT04496687


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