RecruitingNCT04690972

"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".


Sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Enrollment

800 participants

Start Date

Jan 14, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Development of preclinical translational models for chronic liver tumors and diseases study, such as spheroids cultured in autologous medium and murine xenograft models to test the efficacy of new therapeutic strategies.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This is a biological sample collection study (biobank) at a French hospital. Researchers are collecting tissue and biological samples from patients with chronic liver disease or liver tumors during procedures already planned as part of their routine care, in order to build laboratory models to study liver cancer and disease. **You may be eligible if...** - You are an adult with a chronic liver disease (viral or other cause) - You are scheduled for a liver biopsy, liver surgery, or a local treatment for hepatocellular carcinoma (liver cancer) as part of your routine care - You understand the study and give written consent - You are enrolled in the French social security system **You may NOT be eligible if...** - You are under 18 - You are under legal protection or cannot give informed consent independently - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBlood sample during surgery

During the hepato-bilio-pancreatic surgery, blood is drawn.

PROCEDURETaking an additional biopsy

As part of the treatment, an additional biopsy is executed and blood is drawn.

DIAGNOSTIC_TESTBlood sample during diagnostic test

Blood sample as part of the care


Locations(1)

PU-PH, Directeur de l'UMR_S1110 Unité Inserm d'affiliation : UMR_S1110

Strasbourg, France

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NCT04690972


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