RecruitingPhase 2NCT04870762

Customized 3D Printed Oral Stents During Head and Neck Radiotherapy

A Randomized Study of Head and Neck Radiotherapy With or Without Customized 3D Printed Oral Stents


Sponsor

M.D. Anderson Cancer Center

Enrollment

119 participants

Start Date

May 26, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial studies the effect of customized 3 dimensional (3D) printed oral tents on patients with head and neck cancer who are receiving radiotherapy. Oral stents are made from the impression of patients' mouth and cover patients' teeth and gums during radiation therapy. A customized, 3D-printed oral stent may help to reduce mouth blisters and/or sores that may develop in patients while receiving head and neck radiation therapy.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Participant is dispositioned to receive 5-7 weeks of definitive or adjuvant radiotherapy for treatment of a diagnosed head and neck malignancy
  • Age 18 or older
  • ECOG PS 0-2
  • The participant will receive either (a) radiation alone or (b) radiation with concurrent chemotherapy of any kind(s)
  • Signed study-specific consent form

Exclusion Criteria7

  • Prior head and neck radiotherapy
  • Participants is unable to fit a tongue-lateralizing or tongue-depressing stent
  • Severe trismus with an incisal opening of \<10 mm
  • Inability to comply with the study procedures
  • Participants younger than 18 years of age
  • Participants must not be pregnant
  • Cognitively impaired subjects

Interventions

OTHERBest Practice

Receive standard of care

OTHERMedical Device Usage and Evaluation

Wear 3D printed oral stent


Locations(7)

Banner Health/Banner Research

Phoenix, Arizona, United States

Baptist MD Anderson Cancer Center

Jacksonville, Florida, United States

Community MD Anderson Cancer Center East

Indianapolis, Indiana, United States

Community MD Anderson Cancer Center South

Indianapolis, Indiana, United States

Community MD Anderson Cancer Center North

Indianapolis, Indiana, United States

Cooper Hospital University Medical Center

Camden, New Jersey, United States

M D Anderson Cancer Center

Houston, Texas, United States

View Full Details on ClinicalTrials.gov

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NCT04870762


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