RecruitingNot ApplicableNCT05633693

Postural Sway and Counterpressure Maneuvers for Pediatric Syncope

Impact of Postural Sway on Cardiovascular Control in Pediatric Patients With Syncope


Sponsor

Simon Fraser University

Enrollment

30 participants

Start Date

Apr 17, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The investigators are interested in whether discrete counterpressure maneuvers, or muscle movements in the lower body, will boost blood pressure and cardiovascular control in children who faint. We will record cardiovascular responses to maneuvers of exaggerated sway, leg crossing, crouching, and gluteal muscle tensing in children who faint (N=20), as well as their height, weight, muscularity, and pubertal (Tanner) stage. Autonomic cardiovascular control will be measured using a Valsalva manoeuvre (expiration against a closed airway for 20 seconds) and a supine-stand test. The primary outcomes are noninvasive measures of cardiovascular responses to the maneuvers (blood pressure, cerebral blood flow, and stroke volume (volume of blood pumped per heartbeat). Comparisons will be made across levels of sex, diagnosis, Tanner stage, muscularity, height, and degree of autonomic control.


Eligibility

Min Age: 6 YearsMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing physical maneuvers — including postural sway (gentle rocking movements) and counterpressure techniques (like leg crossing or hand gripping) — to help children and teenagers who experience recurrent fainting episodes (vasovagal syncope or POTS-related fainting). These simple exercises may help prevent or stop fainting before it happens. You may be eligible if: - You are between 6 and 18 years old - You have had at least 2 fainting or near-fainting episodes in the past year - Your fainting has been diagnosed as vasovagal syncope or related to POTS by a pediatric cardiologist - You speak English - You have received full COVID-19 vaccination per Health Canada guidelines You may NOT be eligible if: - You have a known cardiac arrhythmia, structural heart disease, or cardiovascular disease - You have had a head injury or seizure disorder - You have diabetes, hypertension, hypoglycemia, or kidney disease - You are taking cardiovascular or syncope medications (e.g., beta-blockers, midodrine, fludrocortisone) - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BEHAVIORALCounterpressure Maneuvers

Movements that can aid in delaying or preventing syncope by recruiting skeletal muscle pumping (via compression of major veins by contracting muscle to eject blood through cardiovascular circuit) and increased sympathetic drive (via sustaining an isometric muscle contraction). In this trial, we will be evaluating two clinically recommended isometric maneuvers (crouching, and leg crossing with muscle tensing) and two novel dynamic maneuvers that comprise discrete movement that the investigators have identified in prior work (exaggerated anterior-posterior postural sway, rhythmic gluteal clenching).

BEHAVIORALBaseline Stand

Participants will stand quietly for 5-minutes on a force platform to allow the investigators to assess their typical response to orthostasis.


Locations(1)

Simon Fraser University

Burnaby, British Columbia, Canada

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05633693


Related Trials