Effect of Magnesium Sulfate Bolus on Intraoperative Neuromonitoring
Randomized and Placebo Controlled Study to Evaluate the Effect of Magnesium Sulfate on Intraoperative Neuromonitoring.
Loma Linda University
50 participants
Mar 18, 2022
INTERVENTIONAL
Conditions
Summary
Magnesium Sulfate(MgSo4) is increasingly being used as part of the multimodal pain regimen in the perioperative period. The intraoperative neurophysiological monitoring (IONM) is utilized in complex spine and cranial surgeries to assess the functional integrity of the neural pathways. The effect of Magnesium sulfate on IONM has not been studied. This is a prospective, double blind, randomized placebo controlled trial to study the effect of Magnesium sulfate bolus on the amplitude and latency of somatosensory(SSEPs) and motor evoked potentials(MEPs) in patients undergoing surgery requiring IONM.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
Effect of 40mg/kg Magnesium sulfate bolus dosed to ideal body weight on intraoperative neuromonitoring
20 ml of normal saline bolus will be administered to the control group over 10 mins.
Locations(1)
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NCT04938765