Magnesium Sulfate and Postoperative Hypercoagulability in Laparoscopic Gynecological Surgeries
Effect of Magnesium Sulfate on Postoperative Hypercoagulability Using Thromboelastometry in Laparoscopic Gynecological Surgeries
Marianna Mavromati
60 participants
Dec 1, 2024
INTERVENTIONAL
Conditions
Summary
This will be a prospective randomized, double-blind study, aiming at investigating the effects of magnesium sulfate on postoperative hypercoagulability in patients undergoing laparoscopic gynecological surgeries under general anesthesia
Eligibility
Inclusion Criteria5
- ASA I and II patients
- Laparoscopic gynecological surgeries
- age \>18 years
- Patients receiving prophylactic anticoagulant therapy 12 hours before surgery based on the Caprini score
- Patients receiving prophylactic anticoagulant therapy 12 hours postoperatively based on the Caprini score.
Exclusion Criteria8
- ASA ≥ III
- age \<18 years
- BMI \>40 kg/m²
- Pregnancy
- Known hematologic disorders
- Liver/kidney/cardiovascular disease
- Severe anemia (6,5- 7,9 g/dl)
- Inability or refusal to provide informed consent
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Interventions
In patients allocated to the MS group, a fixed dose of magnesium sulfate diluted in a fixed volume of natural saline will be administered intravenously. Thromboelastometry will be performed pre and post magnesium administration.
In patients allocated to the NS group, a fixed dose of natural saline will be administered intravenously, through a fixed volume of solution. Thromboelastometry will be performed pre and post magnesium administration.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06717490