RecruitingNCT05017142

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

Swiss Pediatric Inflammatory Bain Disease Cohort Study

Sponsor

University of Bern

Enrollment

500 participants

Start Date

Apr 14, 2020

Study Type

OBSERVATIONAL

Conditions

Multiple Sclerosis Optic Neuritis Transverse Myelitis Acute Disseminated Encephalomyelitis Neuromyelitis Optica Spectrum Disorder Anti-NMDAR Encephalitis Anti-GAD65 Associated Autoimmune Encephalitis Anti-AMPAR-1/2 Associated Autoimmune Encephalitis Anti-Lgi-1 Associated Autoimmune Encephalitis Anti-CASPR-2 Associated Autoimmune Encephalitis Anti-GABAR-1/2 Associated Autoimmune Encephalitis Onconeuronal Antibody (Hu, Ri, Yo, Amphiphysin, CRMP-5, Ma-1, Ma-2, SOX-1) Associated Autoimmune Encephalitis Hashimoto Encephalitis CNS Vasculitis CNS Sarcoidosis CNS Lupus Rasmussen Encephalitis Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)

Summary

The Swiss-Ped-IBrainD is a national patient registry that collects information on diagnosis, symptoms, treatment, and follow-up of pediatric patients with an inflammatory brain disease in Switzerland. It was first implemented in 2020 in the pediatric clinic of the university hospital in Bern. Further centers all over Switzerland opened for recruitment after that: Aarau, Basel, Bellinzona, Chur, Geneva, Lausanne, Lucerne, St. Gallen, Winterthur and Zurich. The center in Fribourg is expected open for recruitment in 2025. The registry provides data for national and international monitoring and research. It supports research on inflammatory brain diseases in Switzerland and the exchange of knowledge between clinicians, researchers, and therapists. The registry aims to improve the treatment of children with inflammatory brain diseases and optimizing their health care and quality of life.

Eligibility

Max Age: 36 Years

Plain Language Summary

Simplified for easier understanding

This is a registry study in Switzerland collecting data on children and teenagers with inflammatory brain diseases — conditions where the immune system mistakenly attacks the brain or spinal cord. The registry aims to improve understanding and treatment of these rare conditions. **You may be eligible if...** - You live or are being treated in Switzerland - You were diagnosed before age 18 with an inflammatory brain condition (such as multiple sclerosis, optic neuritis, transverse myelitis, encephalomyelitis, neuromyelitis optica, or related disorders) - Your diagnosis was made in 2005 or later - You (or your legal guardian) are willing to provide written informed consent **You may NOT be eligible if...** - You were diagnosed after age 18 - Your condition does not fall within the listed inflammatory brain diseases - You do not consent to participation - You are not being treated or living in Switzerland Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(13)

Kantonsspital Aarau

Aarau, Canton of Aargau, Switzerland

Children's Hospital of Eastern Switzerland

Sankt Gallen, Canton of St. Gallen, Switzerland

University Children's Hospital Lausanne (CHUV)

Lausanne, Canton of Vaud, Switzerland

Kantonsspital Winterthur

Winterthur, Canton of Zurich, Switzerland

Pediatric Institute of Southern Switzerland, Ospedale San Giovanni

Bellinzona, Canton Ticino, Switzerland

Kantonsspital Graubünden

Chur, Kanton Graubünden, Switzerland

University Children's Hospital Basel, UKBB

Basel, Switzerland

University Children's Hospital, Inselspital Bern

Bern, Switzerland

Institute of Social and Preventive Medicine, University of Bern

Bern, Switzerland

Hôpital Fribourgeois - Freiburger Spital

Fribourg, Switzerland

University Hospitals of Geneva (HUG)

Geneva, Switzerland

Kinderspital Zentralschweiz

Lucerne, Switzerland

University Children's Hospital Zurich

Zurich, Switzerland

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NCT05017142

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