Deep Brain Stimulation Clinical Trials

30 recruiting

Deep Brain Stimulation Trials at a Glance

33 actively recruiting trials for deep brain stimulation are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 22 trials, with the heaviest enrollment activity in Beijing, Charleston, and Amsterdam. Lead sponsors running deep brain stimulation studies include Beijing Tiantan Hospital, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), and University of Minnesota.

Browse deep brain stimulation trials by phase

Treatments under study

About Deep Brain Stimulation Clinical Trials

Looking for clinical trials for Deep Brain Stimulation? There are currently 30 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Deep Brain Stimulation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Deep Brain Stimulation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 33 trials

Recruiting
Phase 2Phase 3

A Study of Buntanetap in Participants With PD

Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled27 locationsNCT07284784
Recruiting
Not Applicable

Low Intensity Focused Ultrasound for Mild Cognitive Impairment and Mild Alzheimer's Disease

Deep Brain StimulationMild Cognitive ImpairmentMild Alzheimer's Disease+1 more
University of California, Los Angeles144 enrolled1 locationNCT05417555
Recruiting

Udall Project 1 Aim 4

Deep Brain StimulationParkinsons Disease
University of Minnesota100 enrolled1 locationNCT05568199
Recruiting
Not Applicable

Testing of an Interface for Synchronizing tACS-DBS With a Phase-locked-loop

Deep Brain StimulationParkinson's Disease (PD)
Universitätsklinikum Hamburg-Eppendorf2 enrolled1 locationNCT07139093
Recruiting

A Multicenter Pediatric Deep Brain Stimulation Registry

Movement DisordersNeurologic DisorderCerebral Palsy+6 more
Boston Children's Hospital100 enrolled1 locationNCT06585618
Recruiting
Not Applicable

Sleep-specific DBS Therapy in Parkinson's Disease

DystoniaDeep Brain StimulationParkinson's Disease and Parkinsonism
University of Minnesota64 enrolled1 locationNCT05962489
Recruiting
Not Applicable

Use of CereGate Therapy for Freezing of Gait in PD

Parkinson DiseaseDeep Brain StimulationFreezing of Gait
CereGate Inc.41 enrolled7 locationsNCT05292794
Recruiting

Predictors of Clinical Outcomes of Deep Brain Stimulation in Parkinson's Disease

Deep Brain StimulationPARKINSON DISEASE (Disorder)
Hong Kong University of Science and Technology30 enrolled1 locationNCT07376278
Recruiting
Not Applicable

LIFUS For Neurological Disorders

EpilepsyDystoniaDeep Brain Stimulation+4 more
University Health Network, Toronto50 enrolled1 locationNCT07417280
Recruiting
Not Applicable

Adaptive vs. Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease

Parkinson DiseaseDeep Brain Stimulation
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)130 enrolled4 locationsNCT06909045
Recruiting
Not Applicable

Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia

DystoniaDeep Brain StimulationPediatric
Children's Hospital Medical Center, Cincinnati75 enrolled1 locationNCT07325175
Recruiting
Not Applicable

Revision of Deep Brain Stimulator in Patients With Parkinson's Disease

Pain ManagementRegional AnesthesiaDeep Brain Stimulation+1 more
Ankara Etlik City Hospital50 enrolled1 locationNCT07176494
Recruiting
Not Applicable

Effect of Mediterranean Diet on Nutrition in Parkinson's Disease Patients With Bilateral Subthalamic Deep Brain Stimulation

Parkinson DiseaseDeep Brain StimulationDeep Brain Stimulation Surgery
Ankara University24 enrolled1 locationNCT07187739
Recruiting
Early Phase 1

Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

Refractory EpilepsyDeep Brain Stimulation
University of Minnesota20 enrolled1 locationNCT05493722
Recruiting

Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study

Parkinson DiseaseDeep Brain Stimulation
Medical University of South Carolina55 enrolled1 locationNCT06960096
Recruiting

EEG Measurements to Capture DBS-induced Electric Potentials

Deep Brain StimulationParkinson's Disease
Universitätsklinikum Hamburg-Eppendorf20 enrolled1 locationNCT07115394
Recruiting
Phase 4

Imaging Biomarkers of FOG Response to DBS

Deep Brain StimulationFreezing of Gait Symptoms in Parkinson's Disease
Medical University of South Carolina54 enrolled1 locationNCT06951906
Recruiting

The STEREO-DBS Study: 7-Tesla MRI Brain Network Analysis for Deep Brain Stimulation

Treatment OutcomeParkinson DiseaseDeep Brain Stimulation+4 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)500 enrolled1 locationNCT05843084
Recruiting
Not Applicable

Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression

Treatment Resistant DepressionUndergoing Deep Brain Stimulation (DBS) Surgery
Nader Pouratian12 enrolled1 locationNCT03952962
Recruiting
Not Applicable

Impact of Frequency-specific Subthalamic Nucleus Subregion Stimulation on Inhibitory Control in Parkinson's Disease

Parkinson DiseaseDeep Brain Stimulation
Beijing Tiantan Hospital20 enrolled1 locationNCT07022522