RecruitingNot ApplicableNCT05305482

DCS Versus DES for One-month DAPT in Patients With ACS: ONE-PASS Trial

Drug-Coated Stent Versus Drug-Eluting Stent for One-month Dual-antiplatelet Therapy in Patients With Acute Coronary Syndrome: ONE-PASS Trial

Sponsor

Yonsei University

Enrollment

3,520 participants

Start Date

Aug 10, 2022

Study Type

INTERVENTIONAL

Conditions

Acute Coronary Syndrome

Summary

To test whether the polymer-free drug-coated stent (DCS) BioFreedom is noninferior to the biodegradable polymer drug-eluting stent (DES) Ultimaster in terms of 1-year patient-oriented composite endpoint (POCE, composite of all-cause mortality, any MI, or any revascularization) in a setting of 1-month dual-antiplatelet therapy (DAPT) strategy (1-month DAPT followed ticagrelor monotherapy) after acute coronary syndrome.

Eligibility

Min Age: 19 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Drug-coated stent and a medical device called Drug-eluting stent for people with acute coronary syndrome. The study is currently recruiting participants at 1 location. People eligible for this study include aged 19 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEDrug-coated stent

The polymer-free drug-coated stent (BioFreedom Ultra stent) will be implanted for the DCS group.

DEVICEDrug-eluting stent

The Biodegradable polymer drug-eluting stent (Ultimaster stent) will be implanted for the DES group.

Locations(1)

Yonsei Cardiovascular Hospital, Yonsei University College of Medicine

Seoul, South Korea

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NCT05305482

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