Portal Hypertension Clinical Trials

33 recruiting

Frequently Asked Questions

Common questions about Portal Hypertension clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 47 trials

Recruiting

Natural History of Noncirrhotic Portal Hypertension

Cystic FibrosisTurner SyndromeImmunologic Deficiency Syndrome+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)400 enrolled1 locationNCT02417740
Recruiting

Indicators Affecting PVT Recanalization

CirrhosisPortal Hypertension Related to CirrhosisPortal Vein Thrombosis+1 more
Shanghai Zhongshan Hospital1,500 enrolled1 locationNCT07473375
Recruiting

Exploration of Systemic and Portal Hemostasis in Patients Undergoing Transjugular Intrahepatic Portosystemic Shunt Placement

Liver CirrhosisPortal Hypertension
Assistance Publique - Hôpitaux de Paris45 enrolled1 locationNCT07439939
Recruiting
Not Applicable

Hepatic Venous Pressure Gradient Versus Endoscopic Ultrasound-Guided Portal Pressure Gradient - Comparative Analysis (HEPCA)

CirrhosisPortal HypertensionNon-Cirrhotic Portal Hypertension+3 more
Military University Hospital, Prague40 enrolled2 locationsNCT07424963
Recruiting

Construction of a Portal Hypertension Biobank

Portal HypertensionVariceal Bleeding
Shanghai Zhongshan Hospital1,000 enrolled1 locationNCT07419724
Recruiting

3D-MRE and 2D-MRE for Assessing Cirrhosis and Portal Hypertension

CirrhosisLiver Portal Hypertension
Shengjing Hospital100 enrolled1 locationNCT06205992
Recruiting

3D-MRE for Assessing Cirrhosis, Advanced Chronic Liver Disease and Portal Hypertension

Cirrhosis, LiverAdvanced Chronic Liver DiseasePortal Hypertension
Shengjing Hospital150 enrolled1 locationNCT05475015
Recruiting
Not Applicable

Effect of Handgrip Strength on Portal Vein Hemodynamics in Patients With Liver Cirrhosis

Liver CirrhosisPortal Hypertension
Shanxi Provincial People's Hospital120 enrolled2 locationsNCT07116096
Recruiting
Phase 4

Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

Portal Hypertension Related to CirrhosisLiver CirrhosesTIPS+1 more
The Cleveland Clinic70 enrolled1 locationNCT07058155
Recruiting
Not Applicable

Effectiveness and Safety of TIPS Stent Graft in the Treatment of Cirrhosis and Complications of Portal Hypertension

Portal Hypertension Related to CirrhosisVariceal BleedingAscites Hepatic
C. R. Bard166 enrolled1 locationNCT06669806
Recruiting

A Comparative Study of MRI and Ultrasound for Detection of Primary Hepatocellular Carcinoma, Body Composition and Risk Factors for Decompensation in Liver Cirrhosis

MRIUltrasoundHepatocellular Carcinoma (HCC)+3 more
Mattias Ekstedt600 enrolled1 locationNCT07291141
Recruiting
Not Applicable

Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension

Portal Hypertension
Mayo Clinic60 enrolled3 locationsNCT06797193
Recruiting
Not Applicable

TIPS With or Without BCAA

SarcopeniaCirrhosisPortal Hypertension Related to Cirrhosis+2 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology164 enrolled1 locationNCT07281846
Recruiting

2D-shear Wave Spleen Elastography in Clinically Significant Portal Hypertension and High-risk Varices

Portal Hypertension Related to CirrhosisEsophageal Varices
Fondazione Policlinico Universitario Agostino Gemelli IRCCS450 enrolled1 locationNCT07122622
Recruiting

TIPS for Complicated Portal Hypertension Related to Porto-Sinusoidal Vascular Disease

Esophageal VaricesPortal HypertensionTIPS+3 more
Centre Hospitalier Universitaire, Amiens360 enrolled1 locationNCT07163689
Recruiting

Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis

Liver CirrhosisPortal HypertensionHepatic Cell Carcinoma
Massachusetts General Hospital45 enrolled1 locationNCT06265272
Recruiting

VICIS - Vienna Cirrhosis Study

AscitesLiver CirrhosisPortal Hypertension+2 more
Medical University of Vienna10,000 enrolled1 locationNCT03267615
Recruiting
Not Applicable

CARPEUS : Effect of Carvedilol on the Portosystemic Gradient as Measured by Endoscopic Ultrasound

CirrhosisPortal Hypertension Related to Cirrhosis
University Hospital, Clermont-Ferrand30 enrolled2 locationsNCT06861075
Recruiting

hepatomiR cACLD Study

Portal HypertensionChronic Liver Disease and CirrhosisChronic Liver Disease
Karl Landsteiner University of Health Sciences156 enrolled1 locationNCT06432582
Recruiting

Safety of Discontinuing NSBBs in Cirrhotic Patients With Managed Primary Aetiological Factors

CirrhosisPortal HypertensionVarices, Esophageal
Chinese University of Hong Kong375 enrolled8 locationsNCT06549673