Ablation of Arteries for the Treatment of Type 2 Diabetes Mellitus and Its Comorbidities

This study is testing a minimally invasive catheter procedure that uses heat (radiofrequency energy) to treat nerves around arteries (renal and hepatic) as a new approach to controlling both type 2 diabetes and high blood pressure at the same time. Researchers want to see if disrupting these nerve signals improves blood sugar and blood pressure control. **You may be eligible if...** - You are 21–65 years old - You have type 2 diabetes diagnosed within the past 10 years, with HbA1c between 7–9% - You are on metformin and possibly one other oral diabetes drug - You also have high blood pressure (systolic above 140 mmHg) controlled by up to 3 medications - Your BMI is between 27.5 and 40 **You may NOT be eligible if...** - You have type 1 diabetes or need insulin - Your HbA1c is above 9% - You are on beta-blockers or alpha-blockers - You have been hospitalized for dangerously high blood sugar in the past 6 months - You have severe diabetes complications (proliferative retinopathy or peripheral neuropathy) - You have kidney disease (eGFR below 60), liver disease, or a prior kidney/liver transplant - You have severe heart or blood vessel disease - You are pregnant or planning to become pregnant in the next year Talk to your doctor to see if this trial is right for you.