RecruitingPhase 2NCT05389930

Cannabis' Impact on Alcohol Consumption

Cannabis' Impact on Alcohol Consumption: Integrating Laboratory and Ecological Momentary Assessment Methods


Sponsor

Brown University

Enrollment

350 participants

Start Date

Mar 16, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which participants choose either to drink or receive monetary reinforcement for drinks not consumed. Cannabis will be administered simultaneously with an alcohol-priming dose or alcohol placebo. The study will enroll up to 350 nontreatment-seeking heavy episodic alcohol drinkers who use cannabis weekly.


Eligibility

Min Age: 21 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Alcohol, a drug called Alcohol placebo, and others for people with alcohol drinking, alcohol use disorder, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGTHC-dominant cannabis

Smoked cannabis with 9.53% THC and 0.09% CBD

DRUGCBD-dominant cannabis

Smoked cannabis with 0.35% THC and 11.27% CBD

DRUGCannabis placebo

Smoked placebo cannabis plant material

DRUGAlcohol

Drink containing 0.3 g/kg of alcohol

DRUGAlcohol placebo

Placebo beverage contains only juice and a negligible trace of alcohol for masking


Locations(1)

Brown University

Providence, Rhode Island, United States

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NCT05389930


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