Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock

This study is looking at how a temporary heart-lung bypass machine called VA-ECMO (veno-arterial extracorporeal membrane oxygenation) affects the left side of the heart during cardiogenic shock — a life-threatening condition where the heart suddenly cannot pump enough blood. The goal is to better understand how the heart responds to this support and improve how it is used. **You may be eligible if:** - You are between 18 and 75 years old - You are experiencing severe cardiogenic shock (SCAI Stage D or E) and require VA-ECMO - Your shock was caused by a heart attack (acute coronary syndrome) - Your blood pressure is above 65 mmHg on fewer than 3 medications **You may NOT be eligible if:** - Your shock is caused by something other than a heart attack (e.g., sepsis, pulmonary embolism, COVID-19) - You have pre-existing severe heart failure with a history of or evaluation for a heart pump device or transplant - You have severe aortic valve problems - You have active bleeding, limb ischemia, clotting in the ECMO circuit, or infection - You have a blood clot in the left heart chamber Talk to your doctor to see if this trial is right for you.