RecruitingNot ApplicableNCT05442671

iTONE Trial (exercIse Training in pulmONary hypertEnsion) Exercise Program for Pediatric PH

Home Exercise Training in Pediatric Pulmonary Hypertension

Sponsor

Children's Hospital of Philadelphia

Enrollment

25 participants

Start Date

Apr 3, 2024

Study Type

INTERVENTIONAL

Conditions

Pulmonary Hypertension

Summary

Children with pulmonary hypertension (PH) engage in less physical activity than their peers. This is a concern since adult data support exercise as a non-pharmacologic treatment for PH. Despite adult data, therapeutic exercise has not been widely adopted in pediatric PH. Investigators have previously demonstrated that children with PH have less skeletal muscle mass in association with worse exercise performance. Interventions to increase physical activity and skeletal muscle mass may improve exercise performance and quality of life in children with PH. This study will use wearable activity monitoring devices to promote physical activity in a 16-week pilot intervention in children and teenager with PH.

Eligibility

Min Age: 8 YearsMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a home-based exercise program, delivered virtually, for children and teenagers with pulmonary hypertension (high blood pressure in the lungs) to see if it is safe and can improve their fitness and quality of life. **You may be eligible if...** - You are between 8 and 18 years old - You have been diagnosed with pulmonary hypertension (any of the four main types) - Your pulmonary hypertension is classified as mild (WHO functional class I or II) - You are ambulatory (able to walk) - Your medication has been stable for at least 3 months - Your family has WiFi and a device that can receive text messages **You may NOT be eligible if...** - Your pulmonary hypertension is severe (WHO functional class III or IV) - You have a single-ventricle heart condition - You have moderate to severe kidney or liver disease - You have severe exercise-induced low blood pressure Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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