3D-MRE for Assessing Cirrhosis, Advanced Chronic Liver Disease and Portal Hypertension

This study is testing a 3D MRI technique called 3D-MRE (magnetic resonance elastography) that measures liver stiffness non-invasively to see if it can accurately replace an invasive procedure that directly measures blood pressure in the liver (called HVPG), used to assess how advanced liver disease is. **You may be eligible if...** - You are 18 or older and have been diagnosed with advanced chronic liver disease (cirrhosis or severe liver scarring) of any cause - You are already scheduled to have an HVPG measurement (an invasive liver pressure test) as part of your standard care - You can have an MRI performed within one month before your HVPG test **You may NOT be eligible if...** - You have liver cancer or other tumors affecting the area being measured - You have a contraindication to MRI (such as a pacemaker or metal implants) - You have had previous liver or spleen surgery affecting measurement accuracy - You have bile duct blockage or dilation visible on MRI Talk to your doctor to see if this trial is right for you.