Short-term Clinical Outcome of Cortical Bone Trajectory Compared With the Traditional "Open" and Minimal Invasive Posterior Lumbar Interbody Fusion

This study compares three surgical techniques for a spine surgery called posterior lumbar interbody fusion (PLIF): a traditional open approach, a minimally invasive approach, and a newer technique called cortical bone trajectory (CBT). The goal is to find out which method leads to the best short-term outcomes for patients with certain types of spine problems. You may be eligible if: - You are between 18 and 75 years old - You have degenerative or spondylolytic spondylolisthesis (a slipped vertebra) - You have nerve-related leg pain or claudication that has persisted for more than 3 months - Your spondylolisthesis is low-grade (Meyerding grade I or II) You may NOT be eligible if: - You have previously had spine fusion surgery at the same level - You have osteoporosis - You have active cancer or active infection at the surgery site - You are pregnant - You have severe obesity (BMI over 40) or severe psychiatric/substance disorders - You have more than one level of the spine that needs to be fused Talk to your doctor to see if this trial is right for you.