RecruitingNot ApplicableNCT05559749

Collaborative Care for Anxiety and Depression in Epilepsy

Collaborative Care to Improve Quality of Life for Anxiety and Depression in Epilepsy


Sponsor

Wake Forest University Health Sciences

Enrollment

60 participants

Start Date

May 4, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This is a randomized effectiveness/implementation trial comparing a 24-week neurology-based collaborative care intervention to usual neurology care among 60 adults with epilepsy.


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • Provision of signed and dated Informed Consent Form
  • Stated willingness to comply with all study procedures
  • Males and Females; Age \>= 18 years
  • \* Diagnosis of epilepsy: Epilepsy diagnosis based on neurology clinician impression or EEG findings
  • Anxiety or Depression symptoms
  • Receiving clinical neurological care at Atrium Health

Exclusion Criteria15

  • Current participation in another treatment of intervention study
  • Cognitive limitations precluding completion of Anxiety and Depression self-report instruments on paper, electronically, or by interview
  • Comorbid medical condition with life expectancy less than 6 months
  • Not a good candidate for collaborative care due to:
  • Active ongoing treatment by a psychiatrist
  • Active suicidal ideation
  • History of past suicide attempt and:
  • receiving ongoing psychotherapy OR
  • has seen a psychiatrist in the past year
  • History of suicide attempt in the past year and:
  • currently prescribed 2 or more psychotropic medications for psychiatric indication (not merely as a hypnotic) AND not felt to be a good candidate for collaborative care based on the judgement of the investigators
  • Unstable drug or alcohol abuse
  • For the third Aim (sustainability supplement: intervention only care delivery exploratory study supplement) - the Participants meeting the following criteria may participate
  • individuals who meet the above INC-EXC criteria and have completed the Control Arm of a collaborative care research study - NCT05559749 - NCT05353452 or
  • individuals who meet the above INC-EXC criteria except rather than having a diagnosis of Epilepsy; they have a diagnosis of functional neurological disorder with seizures

Interventions

BEHAVIORALcollaborative care

a 24-week neurology based collaborative care program consisting of: 1. a series of every 2 weeks care management calls by the care manager to evaluate anxiety, depression, seizures and side effects and deliver brief therapy interventions to the participant, and 2. collaborative care conferences including a psychiatrist to generate expert recommendations for anxiety and depression management and communication of recommendations between the care manger, psychiatrist and neurologist.

BEHAVIORALusual neurology care

ongoing usual neurology care, without the addition of the collaborative care program


Locations(1)

Wake Forest University Health Sciences

Winston-Salem, North Carolina, United States

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NCT05559749


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