RecruitingNCT05572710

Avalus European Registry - an Observational Study to Evaluate Safety and Efficacy in a Real World Population


Sponsor

Universitaire Ziekenhuizen KU Leuven

Enrollment

1,000 participants

Start Date

Jun 10, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

This is a prospective, observational, single-arm, multi-center registry of patients undergoing bioprosthetic aortic valve replacement with the Avalus valve. This prospective registry aims to examine the outcome and performance of surgical aortic valve replacement with the Avalus pericardial bioprosthesis.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Clinical indication for replacement of the native or prosthetic aortic valve with a bioprosthesis
  • Age \>= 18 years
  • Patient has been adequately informed of risks and requirements of the registry (which are actually limited since the prosthesis is in full commercial use and only data registration is performed) and is able to provide informed consent for participation in the clinical registry.

Exclusion Criteria2

  • Patient requires salvage surgery (according to EuroSCORE II definitions: "patients requiring cardiopulmonary resuscitation (external cardiac massage) en route to the operating theatre or prior to induction of anaesthesia. This does not include cardiopulmonary resuscitation following induction of anaesthesia")
  • Not been able to provide informed consent

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Locations(19)

UZ Leuven

Leuven, Vlaams-Brabant, Belgium

UCL St Luc

Brussels, Belgium

ZOL

Genk, Belgium

AZ Maria Middelares

Ghent, Belgium

UZ Gent

Ghent, Belgium

Rigshospitalet

Copenhagen, Denmark

Kuopio University Hospital

Kuopio, Finland

CHU Nantes

Nantes, France

Schüchtermann-Klinik

Bad Rothenfelde, Germany

Universität Herzzentrum

Hamburg, Germany

Osp. S.Orsola Malpighi

Bologna, Italy

Fondazione Poliambulanza

Brescia, Italy

Villa Maria Cecilia

Cotignola, Italy

Policlinico San Donato S.P.A

Milan, Italy

European Hospital

Roma, Italy

A. Sanitaria O. Ordine Mauriziano

Torino, Italy

UMC Maastricht

Maastricht, Netherlands

Hospital Rambla

Santa Cruz de Tenerife, Spain

Hospital Clinico De Valladolid

Valladolid, Spain

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NCT05572710


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