Avalus European Registry - an Observational Study to Evaluate Safety and Efficacy in a Real World Population

This is a real-world registry study tracking the safety and effectiveness of the Avalus aortic valve bioprosthesis — a tissue replacement valve for the aorta — in patients undergoing aortic valve replacement surgery at participating hospitals across Europe. Unlike a controlled trial, this registry observes how the valve performs in normal clinical practice with diverse patients. You may be eligible if: - You are 18 years of age or older - You have a clinical need to replace your aortic valve (native or previously implanted prosthesis) with a bioprosthesis - You have been adequately informed about the registry and can provide informed consent You may NOT be eligible if: - You require emergency salvage surgery (involving CPR while being transported to the operating room) - You are unable to provide informed consent Talk to your doctor to see if this trial is right for you.