RecruitingNCT05647135

ImpACt of Very High Protein Content Enteral nUtrition Formulas on Critically Ill MUltipLe trAuma paTiEnts

ImpACt of Very High Protein Content Enteral nUtrition Formulas on Protein Metabolism and Residual Gastric Volume in Critically Ill MUltipLe trAuma paTiEnts


Sponsor

Romanian Society for Enteral and Parenteral Nutrition

Enrollment

70 participants

Start Date

Mar 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This prospective observational randomized study aims to determine energy, protein intake and gastrointestinal tolerance while using enteral nutrition formulas with very high protein content and enteral nutrition formulas with normal protein content. * Differences regarding achieving protein and calorie daily targets when using enteral nutrition formulas with different protein content * Differences regarding residual gastric volume when using enteral nutrition formulas with different protein content * Differences regarding body composition when using enteral nutrition formulas with different protein content


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Adult patients (\>18 yrs) admitted to the ICU
  • Multiple trauma (Injury severity score \> 18)
  • Intubation and mechanical ventilation upon admission in ICU or during the first 24 hours of admission, for at least 48 h

Exclusion Criteria6

  • Age \< 18 years
  • Pregnant women
  • Patients not intubated or not mechanically ventilated or receiving only non-invasive ventilation
  • Patients with enteral feeding contraindication 48 h after admission
  • Patients with recent gastrointestinal surgical intervention
  • Patients on chronic therapy with corticosteroids

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Interventions

OTHERMedical food

enteral formulas with different protein composition


Locations(1)

Clinical Emergency Hospital of Bucharest

Bucharest, Romania

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NCT05647135


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