RecruitingNCT05677607
Feedback Loop Between Intracranial Atherosclerosis and Cerebral Small Vessel Disease
Sponsor
Chinese PLA General Hospital
Enrollment
300 participants
Start Date
Jan 1, 2023
Study Type
OBSERVATIONAL
Conditions
Summary
The present study aims at verifying the mutual effects between intracranial large artery atherosclerosis and cerebral small vessel disease on disease progression and prognosis by magnetic resonance imaging, and providing biomarkers for the early prevention and treatment of cerebrovascular disease.
Eligibility
Min Age: 30 Years
Inclusion Criteria4
- Age ≥ 18 years
- At least one intracranial artery ≥ 50% atherosclerotic stenosis
- Modified Rankin Scale \< 2
- Mini-mental State Examination \> 24
Exclusion Criteria3
- Concurrent ipsilateral extracranial artery ≥ 50% stenosis
- Pregnant women
- Contraindications to magnetic resonance examination (patients with pacemakers, nerve stimulators, artificial metal heart valves and other metal foreign bodies)
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Interventions
DIAGNOSTIC_TESTMagnetic resonance imaging
Imaging diagnostics mainly based on Magnetic resonance imaging.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05677607
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