RecruitingNot ApplicableNCT05684367

Exercise to ReGain Stamina and Energy (The EXERGISE Study)

Center-Based and Home-Based Walking Exercise Intervention to Reduce Fatigue in Older Breast Cancer Survivors

Sponsor

University of Florida

Enrollment

24 participants

Start Date

Nov 29, 2023

Study Type

INTERVENTIONAL

Conditions

Breast Cancer Fatigue Cancer, Therapy-Related

Summary

About 20%-70% of breast cancer survivors experience fatigue after cancer therapy. Because epidemiologic evidence shows that old age is a risk factor for fatigue in adults with cancer history, older breast cancer survivors suffer from even more fatigue than younger survivors. The purpose of this study is to test types of walking exercise interventions and their ability to reduce fatigue in older breast cancer survivors.

Eligibility

Sex: FEMALEMin Age: 60 YearsMax Age: 105 Years

Plain Language Summary

Simplified for easier understanding

This study (EXERGISE) is testing whether an exercise program can reduce cancer-related fatigue and improve energy in older breast cancer survivors who finished treatment within the past year. **You may be eligible if...** - You are 60 years or older - You had stage I, II, or III invasive breast cancer diagnosed in 2021 or 2022 - You completed your main cancer treatment (like chemotherapy or radiation) at least 3 months ago but no more than 1 year ago - You are currently experiencing at least moderate fatigue - You are willing to participate in an exercise program and all study activities **You may NOT be eligible if...** - You are currently enrolled in another rehabilitation or interventional study - You have a medical condition that makes exercise unsafe - You were recently diagnosed with a heart condition, stroke, COPD, diabetes, or kidney disease (within the past 3 years) - You are pregnant - You have significant cognitive impairment or a degenerative nerve disease - You recently took antibiotics or probiotics (within 4 weeks of screening) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALCenter-Based Walking Exercise

Each exercise session will begin with a short warm-up followed by 30 min of walking. Participants will initially be instructed to walk at a moderate intensity, equivalent to a 5-6 on Borg category-ratio (CR) scale. Participants will be encouraged to, if possible, incorporate brief periods of vigorous walking (7-8 on CR10 scale) with a goal of achieving at least 10 min of vigorous walking per session.

BEHAVIORALHome-Based Walking Exercise

Participants will be asked to walk for exercise in their community five days/week. Participants will be instructed to begin with 10-15 minutes of walking exercise/session in the first month of the intervention and to increase exercise duration by five minutes/session each week, facilitating reasonable but steady progress toward the goal of 30 minutes per session.