RecruitingNCT05694624

Investigations Into Sepsis-associated Acute Kidney Injury

Investigations Into the Mechanisms for Bioenergetic Failure in Sepsis-associated Acute Kidney Injury

Sponsor

University Hospital of North Norway

Enrollment

20 participants

Start Date

Aug 14, 2023

Study Type

OBSERVATIONAL

Conditions

Acute Kidney Injury

Summary

In this study the investigators would like to study systemic and regional disturbances in patients with sepsis-associated acute kidney injury and in healthy controls undergoing laparoscopic abdominal surgery. Specifically study metabolic, hemodynamic and oxygen transport variables.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria8

Sepsis diagnosed or suspected
Normal premorbid serum creatinine measured or anticipated (if data are not available)
Normovolemia as indicated by a pulse pressure variation less than 12%
Comparator group
Previously healthy individuals scheduled for laparoscopic colon cancer resection
Normal creatinine levels within 3 months before admittance to hospital.
Patients admitted to the intensive care unit with sepsis diagnosed or suspected
Previously healthy patients listed for elective colon cancer surgery