RecruitingEarly Phase 1NCT05707871

Cardiovascular Effects of Very Low Nicotine Content Cigarettes

Sponsor

Wake Forest University Health Sciences

Enrollment

49 participants

Start Date

Apr 4, 2023

Study Type

INTERVENTIONAL

Conditions

The study is measuring Cardiovascular effects of very low nicotine content cigarettes on daily and non-daily smokers

Min Age: 21 Years

Self-reported cigarette smoking at least once in the past 30 days
≥21 years old
Willingness to smoke research cigarettes or usual brand cigarettes during lab visit.
Ability to speak, comprehend, and read English sufficiently to complete study procedures

Self-reported diagnosis of cardiovascular diseases like coronary artery disease, stroke, peripheral artery disease, cardiac arrhythmia, pulmonary embolism \& blood clots in legs and arm in the past 3 months
Body temperature ≥ 100.4˙F
Unstable health conditions interfering with electrocardiogram (ECG) measurements
Self-reported diagnosis of hyperthyroidism or thyrotoxicosis
Currently pregnant (as indicated by urine pregnancy test at the start of laboratory visit) or breastfeeding.
Currently seeking treatment to quit smoking