RecruitingNCT05725174

Volatile Non-Invasive Biomarkers of Epileptic Seizures

Sponsor

University College London Hospitals

Enrollment

270 participants

Start Date

Jan 30, 2023

Study Type

OBSERVATIONAL

Conditions

Epilepsy Non-Epileptic Seizure

Summary

Breath and sweat samples will be collected from people who have been admitted to hospital after a potential seizure and analysed by the team. The researchers then hope to identify a pattern of small molecules that can distinguish seizures from other events, and perhaps determine the severity of the seizure.

Eligibility

Min Age: 18 Years

Inclusion Criteria2

Patients who have been admitted to either University College London's Queen's Square EEG-telemetry unit or Chalfont Centre for Epilepsy, for diagnosis of seizure events.
Patients aged 18 years or above

Exclusion Criteria4

Patients with active infection or who have taken antibiotics within 4 weeks
Patients on immunosuppressive medications
Patients with co-morbidities preventing breath collection
Patients unable to provide informed consent.

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Interventions

OTHERSample Collection

Patients will have breath samples collected by blowing into a bag, and sweat samples collected by gauze. These samples will be collected at various timepoints whilst the patients are admitted on the ward.