RecruitingNot ApplicableNCT05730309

Point-of-care Ultrasound and Treatment Disparities for Left Ventricular Hypertrophy


Sponsor

Yale University

Enrollment

200 participants

Start Date

Oct 15, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of the proposed project is to quantify the prevalence and disparities of undiagnosed left ventricular hypertrophy (LVH) in Emergency Department (ED) patients with persistently elevated asymptomatic BP, and to measure the effect of disclosure, education, and expedited referral on 3-month outpatient follow-up and treatment rates for ED patients with newly diagnosed LVH by POCUS. Additionally, investigators will create a database of annotated clips for future development of a machine learning algorithm for LVH detection on POCUS.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Two blood pressure measurements greater than 140 mmHg systolic and greater than 90 mmHg diastolic on two separate vital sign checks obtained as part of routine ED care

Exclusion Criteria6

  • Subjects in extremis or lacking capacity to consent
  • Active treatment of hypertension within the last year
  • History of/known left ventricular hypertrophy
  • Active cardiac disease under the care of a cardiologist within last year
  • Suspicion for hypertensive emergency by treating ED physician
  • Admission to the hospital

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Interventions

BEHAVIORALCustomized discharge and expedited referral instructions

The intervention for subjects with LVH on research POCUS will consist of three elements: 1) disclosure of presence of LVH to subject, ED team and primary care physician (PCP) (if applicable); 2) educational discharge instructions describing high BP, HTN, LVH, implications for development of cardiovascular disease (such as development of heart failure, stroke), options for treatment (lifestyle, medications) and importance of follow-up; A preliminary version will be refined prior to the start of the trial by feedback from ED physicians and patients. Refinement will target content, phrasing, and literacy level. 3) referral to outpatient care, consisting of one of two options, based on whether the subject has an established PCP. For subjects with existing PCP, the study team will call the office, inform about study participation, LVH findings, and secure a follow-up appointment. For those with no PCP, study team will arrange for follow-up to special clinic.


Locations(1)

Yale New Haven Hospital

New Haven, Connecticut, United States

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NCT05730309


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