Optimum Induction Therapy of Low-risk APL

This study is looking for the best induction (initial) treatment approach for people newly diagnosed with low-risk acute promyelocytic leukemia (APL), a type of blood cancer that tends to respond well to treatment. Researchers want to compare different treatment combinations to find the safest and most effective option. **You may be eligible if...** - You have been newly diagnosed with APL (a specific type of leukemia) - You are between 18 and 75 years old - Your liver and kidney function are within acceptable limits - Your white blood cell count is not too high at diagnosis - Your overall health allows you to tolerate treatment (ECOG score 0–2) **You may NOT be eligible if...** - You have HIV, active hepatitis B or C, or a serious heart rhythm problem - You are pregnant or breastfeeding - You have a serious mental illness that would affect your ability to participate - You are already enrolled in another clinical trial Talk to your doctor to see if this trial is right for you.