South Africa Smoking Cessation and Engagement in HIV/TB Care Care
Treatment Development for Smoking Cessation and Engagement in HIV/TB
Massachusetts General Hospital
86 participants
Mar 12, 2024
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to integrate elements from existing interventions developed by our team into a single intervention (QUIT-AD), designed to improve smoking cessation and favorable HIV/TB treatment outcomes among individuals with HIV and/or TB in Cape Town, South Africa. If feasibility, acceptability, and preliminary efficacy are demonstrated, the intervention will be ready for large-scale effectiveness/implementation testing. This program will has the potential to dramatically improve public health by increasing the smoking quit rate and facilitating favorable HIV/TB treatment outcomes among patients with HIV and/or TB in resource limited South African settings.
Eligibility
Inclusion Criteria4
- Aged 18 or older
- Willing and able to provide written informed consent
- Living with HIV, confirmed via medical record, and on antiretroviral therapy (ART) AND/OR within 1 month of initiating or reinitiating TB treatment; positive GeneXpert test or sputum culture
- (5) Daily smoker operationalized as \> 5 cigarettes per day, (6) Motivation (\> 5/10) to quit smoking or \> 24 hour quit past yr
Exclusion Criteria5
- Habitual use of other tobacco products
- Current interfering untreated/unstable mental health condition (e.g., psychosis, bipolar dx)
- Current use of non-study pharmacotherapy for smoking cessation,
- Cognitive Behavioral Therapy for smoking cessation initiated within the past year,
- Diagnosed with extra-pulmonary or drug resistant (MDR or XDR) TB based upon chart review
Interventions
An adapted, six-session cognitive behavioral therapy intervention for smoking cessation and treatment adherence
Standard treatment for HIV/TB with one session of psychoeducation.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05842161