Allopurinol Improves Heart Function in African Americans With Resistant Hypertension

This study is testing whether allopurinol — a common gout medication — can improve heart function in African American veterans who have resistant high blood pressure (blood pressure that remains high despite multiple medications). **You may be eligible if...** - You are an African American veteran - You have been diagnosed with resistant hypertension (blood pressure above 140/90 despite taking 3 or more blood pressure medications) - You live in or near Birmingham, Alabama **You may NOT be eligible if...** - You have been diagnosed with heart failure - You have chronic kidney disease with poor kidney function - You are on long-term steroid therapy - You have known coronary artery disease (blocked heart arteries) - You are already taking allopurinol - You have a pacemaker or other cardiac implant (for the MRI component) - You are claustrophobic (for the MRI component) Talk to your doctor to see if this trial is right for you.