Resistant Hypertension Clinical Trials

16 recruiting

Resistant Hypertension Trials at a Glance

16 actively recruiting trials for resistant hypertension are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Rio de Janeiro, Birmingham, and Chengdu. Lead sponsors running resistant hypertension studies include DeepQure Inc., National Institute of Cardiology, Laranjeiras, Brazil, and First Affiliated Hospital of Chengdu Medical College.

Browse resistant hypertension trials by phase

Treatments under study

About Resistant Hypertension Clinical Trials

Looking for clinical trials for Resistant Hypertension? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Resistant Hypertension trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Resistant Hypertension clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 116 of 16 trials

Recruiting
Early Phase 1

Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients

Arterial HypertensionMicrovascular FunctionResistant Hypertension+1 more
National Institute of Cardiology, Laranjeiras, Brazil50 enrolled1 locationNCT06169241
Recruiting
Phase 2

Endothelin-1 Receptor Blockade in Resistant Hypertension

Resistant Hypertension
University Hospital, Rouen24 enrolled1 locationNCT04388124
Recruiting
Not Applicable

Effect of Electrical Stimulation and Exercise on Blood Flow in Patients With Resistant High Blood Pressure

Metabolic SyndromeAbdominal ObesityHigh Blood Pressure+5 more
Mohamed Mohamed Ali Morgan50 enrolled1 locationNCT07383220
Recruiting
Phase 2

Allopurinol Improves Heart Function in African Americans With Resistant Hypertension

Heart Failure Preserved Ejection FractionResistant Hypertension
VA Office of Research and Development50 enrolled1 locationNCT05888233
Recruiting
Not Applicable

Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension

Resistant Hypertension
DeepQure Inc.15 enrolled5 locationsNCT06526858
Recruiting
Not Applicable

A First-in-human Study of HyperQureTM", Laparoscopic Renal Denervation Therapy in Patient With Resistant Hypertension

Resistant Hypertension
DeepQure Inc.10 enrolled7 locationsNCT06216808
Recruiting
Not Applicable

Rapid Management of Resistant Hypertension in the Public Health System (Fast Control)

HypertensionHigh Blood PressureApparent Resistant Hypertension
Instituto Dante Pazzanese de Cardiologia142 enrolled1 locationNCT07259733
Recruiting

Symplicity China Study

Resistant Hypertension
Medtronic Vascular500 enrolled1 locationNCT07081243
Recruiting
Not Applicable

Arterial Stiffness as a Tool to Investigate Adherence in Resistant Hypertension

Resistant Hypertension
Institut National de la Santé Et de la Recherche Médicale, France60 enrolled1 locationNCT07207226
Recruiting
Not Applicable

Effect of Renal Denervation on Bood Pressure in Patients on Hemodialysis

Treatment Resistant HypertensionChronic Hemodialysis
University of Erlangen-Nürnberg Medical School12 enrolled1 locationNCT06556407
Recruiting

Evaluation of Systemic Microvascular Reactivity in Patients With Resistant Hypertension

Endothelial DysfunctionArterial HypertensionResistant Hypertension+1 more
National Institute of Cardiology, Laranjeiras, Brazil150 enrolled1 locationNCT05464849
Recruiting
Phase 2

Endocalyx in Treatment Resistent Hypertension

Treatment Resistant Hypertension
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)64 enrolled1 locationNCT06940011
Recruiting

Resistant Hypertension An Open, Complicated ("Cum Plicare") or Complex ("Cum Plexus") Syndrome?

HypertensionResistant Hypertension
University of Campinas, Brazil80 enrolled1 locationNCT06450327
Recruiting
Not Applicable

Evaluation of Two Isometric Exercises in the Reduction of the Blood Pressure in People With Resistant Hypertension

Resistant Hypertension
Universidade do Porto15 enrolled1 locationNCT06515795
Recruiting

Comparison of Catecholamine Concentrations in Venous Blood During Selective Adrenal Artery Embolization

Primary AldosteronismSecondary HypertensionResistant Hypertension+1 more
First Affiliated Hospital of Chengdu Medical College196 enrolled1 locationNCT06228677
Recruiting
Phase 3

DORADO – Fixed Doses of Darusentan as Compared to Placebo in Resistant Hypertension

Resistant Hypertension
Myogen, inc.350 enrolled1 locationACTRN12606000292572