Advanced Colorectal Carcinoma Clinical Trials

9 recruiting

Advanced Colorectal Carcinoma Trials at a Glance

12 actively recruiting trials for advanced colorectal carcinoma are listed on ClinicalTrialsFinder across 6 cities in 3 countries. The largest study group is Phase 2 with 5 trials, with the heaviest enrollment activity in New York, Sacramento, and Chicago. Lead sponsors running advanced colorectal carcinoma studies include Duke University, Fudan University, and Cancer Institute and Hospital, Chinese Academy of Medical Sciences.

Browse advanced colorectal carcinoma trials by phase

Treatments under study

About Advanced Colorectal Carcinoma Clinical Trials

Looking for clinical trials for Advanced Colorectal Carcinoma? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Advanced Colorectal Carcinoma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Advanced Colorectal Carcinoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Phase 2

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

Advanced Colorectal CarcinomaAdvanced Anal CarcinomaAdvanced Biliary Tract Carcinoma+41 more
Mayo Clinic220 enrolled2 locationsNCT05969860
Recruiting
Phase 1

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast Carcinoma+37 more
National Cancer Institute (NCI)51 enrolled23 locationsNCT04704661
Recruiting
Not Applicable

Engage Psychosocial Intervention for Cancer Symptoms

Advanced Breast CancerAdvanced Prostate CancerAdvanced Lung Cancer+2 more
Duke University190 enrolled1 locationNCT06555588
Recruiting
Phase 1

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

Locally Advanced Gastroesophageal Junction AdenocarcinomaMetastatic Gastroesophageal Junction AdenocarcinomaStage IV Colorectal Cancer AJCC v8+26 more
Roswell Park Cancer Institute45 enrolled1 locationNCT04511039
Recruiting
Phase 2

Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer

Locally Advanced Hepatocellular CarcinomaLocally Advanced Gastric CarcinomaAdvanced Biliary Tract Carcinoma+7 more
OHSU Knight Cancer Institute66 enrolled1 locationNCT05705492
Recruiting

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

Stage IV Lung Cancer AJCC v8Unresectable Lung Non-Small Cell CarcinomaStage IV Pancreatic Cancer AJCC v8+6 more
University of Rochester800 enrolled225 locationsNCT06073431
Recruiting
Phase 2

Immune Checkpoint Inhibitors + Chemotherapy Versus Chemotherapy in the Neoadjuvant Treatment of Locally Advanced Colorectal Cancer

Locally Advanced Colorectal Carcinoma
Cancer Institute and Hospital, Chinese Academy of Medical Sciences170 enrolled3 locationsNCT06154538
Recruiting
Phase 1

The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors

Anatomic Stage III Breast Cancer AJCC v8Advanced Colorectal CarcinomaAdvanced Malignant Solid Neoplasm+4 more
University of California, Davis100 enrolled1 locationNCT05967533
Recruiting
Phase 2

Phase II Study of Serplulimab Combined with First-Line Targeted Therapy, Chemotherapy, and Radiation in Advanced Colorectal Cancer

Advanced Colorectal CarcinomaImmunotherapy
Fudan University208 enrolled10 locationsNCT06521866
Recruiting
Phase 1

First-in-human Phase I Study to Evaluate Safety, Tolerability and Antineoplastic Activity of OATD-02 in Patients with Selected Advanced And/or Metastatic Solid Tumours

Metastatic Renal Cell CarcinomaMetastatic Ovarian CarcinomaMetastatic Pancreatic Carcinoma+5 more
Molecure S.A.40 enrolled3 locationsNCT05759923
Recruiting
Phase 4

Survival Benefit of Compound Kushen Injection in the Treatment of Advanced Colorectal Cancer

Advanced Colorectal Carcinoma
Guang'anmen Hospital of China Academy of Chinese Medical Sciences320 enrolled1 locationNCT05894694
Recruiting
Phase 2

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Metastatic Gastroesophageal Junction Adenocarcinoma+30 more
Northwestern University94 enrolled1 locationNCT05733000