RecruitingNot ApplicableNCT05934162

Efficacy of Internet-delivered Cognitive-behavior Therapy for PTSD

Efficacy and Mediators of Change of Cognitive-behavior Therapy for PTSD: a Randomized Controlled Trial


Sponsor

Karolinska Institutet

Enrollment

286 participants

Start Date

Sep 4, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to compare therapist-guided internet delivered prolonged exposure to an active control condition( therapist-guided internet delivered cognitive behavioral therapy containing relaxation techniques) for post-traumatic stress disorder. The objective with this study is to investigate efficacy, mechanisms of change and cost effectiveness of therapist-guided internet delivered prolonged exposure. Adult patients with post-traumatic stress disorder will be randomly assigned to receive either 10 weeks of therapist-guided internet delivered prolonged exposure or therapist-guided internet delivered cognitive-behavioral therapy containing relaxation.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether internet-based cognitive-behavioral therapy (CBT) — a structured talking therapy delivered online — is effective for treating PTSD (post-traumatic stress disorder). Participants complete therapy exercises through a website or app. **You may be eligible if...** - You are 18 or older - You have a current primary diagnosis of PTSD - You can read and communicate fluently in Swedish - You have daily access to a computer or device with internet - Any psychiatric medication you take has been at a stable dose for at least 4 weeks **You may NOT be eligible if...** - Your PTSD is not the main concern requiring treatment right now - Your psychiatric medication was recently started or changed - You have serious mental health conditions like mania, psychosis, active substance use disorder, or current suicide risk - You are currently receiving another trauma-focused therapy - You are still in an ongoing threatening or dangerous situation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALTherapist-supported internet-delivered prolonged exposure

10 weeks of therapist-supported internet-delivered prolonged exposure

BEHAVIORALTherapist-supported internet-delivered CBT

10 weeks of therapist-supported internet-delivered CBT


Locations(1)

Traumaprogrammet, Psykiatri Sydväst

Stockholm, Sweden

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NCT05934162


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