RecruitingNCT05985525

Microvascular Monitoring in Circulatory Shock and Sepsis (MiMICSS)

Microvascular Monitoring in Circulatory Shock and Sepsis (MiMICSS): Prospective Observational Cohort Study


Sponsor

University of Manitoba

Enrollment

100 participants

Start Date

May 27, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Investigation of the feasibility of using near-infrared spectroscopy (NIRS) to monitor microvascular function in critically ill patients.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Admitted to ICU
  • Receiving invasive mechanical ventilation

Exclusion Criteria8

  • Body Mass Index >40
  • More than 24 hours has elapsed since ICU admission
  • Death is deemed to be imminent and inevitable during the next 24 hours
  • Known allergy to the textile components of the device
  • Significant clinical jaundice, ecchymosis
  • COVID positive microbiological result
  • The treating clinician believes that participation in the domain would not be in the best interests of the patient
  • Consent declined from patient or authorized third party

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Interventions

DEVICESkeletal muscle and cerebral NIRS (research device)

NIRS applied on skeletal muscle and brain on days 1, 3, and 8 of ICU admission. Monitoring applied for up to 24hrs on each day.


Locations(1)

Health Sciences Centre Winnipeg

Winnipeg, Manitoba, Canada

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NCT05985525


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