RecruitingPhase 1NCT06070649
The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
Sponsor
Yale University
Enrollment
63 participants
Start Date
Aug 4, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
This proposed study is a double-blind, randomized, placebo-controlled, parallel-group, laboratory study to determine the effects of DMT, plus psychotherapy, on Alcohol Use Disorder.
Eligibility
Min Age: 21 YearsMax Age: 65 Years
Plain Language Summary
Simplified for easier understanding
This clinical trial is studying a drug called 0.2 mg/kg/min + Dimethyltryptamine 0.01mg/kg/min infusion, a drug called 0.3mg/kg/min Dimethyltryptamine + Normal Saline infusion, and others for people with alcohol use, alcohol use disorder (aud), and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 21 Years to 65 Years.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
DRUG0.3mg/kg/min Dimethyltryptamine + Normal Saline infusion
Infusion
DRUG0.2 mg/kg/min + Dimethyltryptamine 0.01mg/kg/min infusion
Infusion
DRUG25 mg Diphenhydramine (5 min) + Normal Saline
Infusion
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06070649
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