Alcohol Use Clinical Trials

222 recruitingLast updated: May 13, 2026

There are 222 actively recruiting alcohol use clinical trials across 24 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include New Haven, Connecticut, United States, Baltimore, Maryland, United States, Bethesda, Maryland, United States. Updated daily from ClinicalTrials.gov.


Alcohol Use Trials at a Glance

222 actively recruiting trials for alcohol use are listed on ClinicalTrialsFinder across 6 cities in 24 countries. The largest study group is Not Applicable with 116 trials, with the heaviest enrollment activity in New Haven, Baltimore, and Bethesda. Lead sponsors running alcohol use studies include Yale University, National Institute on Alcohol Abuse and Alcoholism (NIAAA), and Medical University of South Carolina.

Browse alcohol use trials by phase

Treatments under study

About Alcohol Use Clinical Trials

Looking for clinical trials for Alcohol Use? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Alcohol Use trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Alcohol Use clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 222 trials

Recruiting
Phase 1

Environment and Alcohol: A Pilot Study

Alcohol Use Disorder
National Institute on Drug Abuse (NIDA)44 enrolled1 locationNCT06860607
Recruiting
Not Applicable

Reducing Hazardous Alcohol Use and Optimizing Treatment as Prevention Among Men Living With HIV in Risk Environments

HIV InfectionsHIV InfectionAlcohol Use Disorder+2 more
San Diego State University716 enrolled1 locationNCT06771843
Recruiting
Phase 2

Semaglutide Therapy for Alcohol Reduction (STAR)

Alcohol Use DisorderAddiction
National Institute on Drug Abuse (NIDA)80 enrolled1 locationNCT06015893
Recruiting
Phase 2

Guanfacine for Alcohol Use Disorder (AUD)

Alcohol Use Disorder
Indiana University200 enrolled2 locationsNCT06629259
Recruiting
Not Applicable

Cerebellar Involvement in Alcohol Use Disorder (AUD)

Alcohol Use Disorder
Johns Hopkins University122 enrolled1 locationNCT05732207
Recruiting
Not Applicable

Assessing the Impact of dTMS on Neural Targets Associated With Alcohol Use Disorder

Alcohol Use Disorder (AUD)Transcranial Magnetic Stimilation
Stanford University100 enrolled1 locationNCT06949423
Recruiting
Phase 1

Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS)

Weight LossAlcohol Use DisorderBariatric Surgery Patients
Yale University10 enrolled1 locationNCT07223983
Recruiting
Not Applicable

Behavioral and Functional Task Development, Implementation, and Testing

AlcoholismAlcohol DrinkingAlcohol Use Disorder+2 more
National Institute on Alcohol Abuse and Alcoholism (NIAAA)400 enrolled1 locationNCT02108054
Recruiting

NIAAA Natural History Protocol

Alcohol Use Disorder
National Institute on Alcohol Abuse and Alcoholism (NIAAA)7,500 enrolled1 locationNCT02231840
Recruiting
Not Applicable

Implementation Facilitation Pilot for Alcohol Use Disorder (AUD) in Alcohol-associated Liver Disease (ALD)

Alcohol Use DisorderAlcohol Associated Liver Disease
Yale University30 enrolled1 locationNCT07525258
Recruiting
Not Applicable

StuDy AimED at Increasing AlCohol AbsTinEnce

Alcohol Use Disorder
University of Illinois at Chicago104 enrolled1 locationNCT05778734
Recruiting
Phase 1Phase 2

Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease

CirrhosisAlcohol Use DisorderLiver Disease; Alcohol-Related
Virginia Commonwealth University80 enrolled2 locationsNCT05548452
Recruiting
Not Applicable

Mobile Platform for Optimizing Wellness and Engagement in Recovery

Opioid-use DisorderAlcohol Use DisorderOpioid Agonist Treatment
University of Michigan50 enrolled1 locationNCT07178990
Recruiting
Phase 2

Human Laboratory Study of Apremilast for Alcohol Use Disorder

Alcohol Use DisorderAlcohol Misuse
National Institute on Alcohol Abuse and Alcoholism (NIAAA)100 enrolled3 locationsNCT07325266
Recruiting
Phase 1

Spironolactone in Alcohol Use Disorder (SAUD)

Alcohol Use Disorder
National Institute on Drug Abuse (NIDA)20 enrolled1 locationNCT05807139
Recruiting
Not Applicable

Enhancing Prospective Thinking in Early Recovery (HOME)

Alcohol Use Disorder
Indiana University500 enrolled1 locationNCT06302413
Recruiting
Phase 2

Brexpiprazole in Alcohol Use Disorder

Alcohol Use Disorder
University of Colorado, Denver250 enrolled1 locationNCT04066192
Recruiting
Not Applicable

College Student Alcohol Behaviors and Strategies

Alcohol Use
University of Wyoming300 enrolled1 locationNCT07156305
Recruiting

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Healthy VolunteerTobacco Use DisorderMigraine+8 more
Yale University200 enrolled2 locationsNCT06624137
Recruiting
Phase 2

Motivation for IV Alcohol Self-Administration in Humans

Alcohol Use Disorder
University of California, Los Angeles210 enrolled1 locationNCT06494891