Alcohol Use Clinical Trials

243 recruitingLast updated: July 25, 2026

There are 243 actively recruiting alcohol use clinical trials across 25 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include New Haven, Connecticut, United States, Bethesda, Maryland, United States, Baltimore, Maryland, United States. Updated daily from ClinicalTrials.gov.


Alcohol Use Trials at a Glance

243 actively recruiting trials for alcohol use are listed on ClinicalTrialsFinder across 6 cities in 25 countries. The largest study group is Not Applicable with 126 trials, with the heaviest enrollment activity in New Haven, Bethesda, and Baltimore. Lead sponsors running alcohol use studies include Yale University, National Institute on Alcohol Abuse and Alcoholism (NIAAA), and Medical University of South Carolina.

Browse alcohol use trials by phase

Treatments under study

About Alcohol Use Clinical Trials

Looking for clinical trials for Alcohol Use? There are currently 19 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Alcohol Use trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Alcohol Use clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 243 trials

Recruiting
Phase 1

Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)

Alcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)176 enrolled1 locationNCT07559500
Recruiting
Phase 1

Environment and Alcohol: A Pilot Study

Alcohol Use Disorder
National Institute on Drug Abuse (NIDA)44 enrolled1 locationNCT06860607
Recruiting

Hepatic Lipid Metabolism-Alcohol Use Disorder

Alcohol Use Disorder
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)25 enrolled1 locationNCT07191561
Recruiting
Phase 2

Tirzepatide in MetALD

Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Phase 1

Spironolactone in Alcohol Use Disorder (SAUD)

Alcohol Use Disorder
National Institute on Drug Abuse (NIDA)20 enrolled1 locationNCT05807139
Recruiting

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

Substance Use DisorderAlcohol Use Disorder
National Institute on Drug Abuse (NIDA)10,000 enrolled1 locationNCT06552741
Recruiting
Phase 2

Semaglutide Therapy for Alcohol Reduction (STAR)

Alcohol Use DisorderAddiction
National Institute on Drug Abuse (NIDA)80 enrolled1 locationNCT06015893
Recruiting
Phase 4

Temporally-Resolved Electrophysiology of Acamprosate Treatment of Alcohol Use Disorder

Alcohol Use Disorder
National Institute on Alcohol Abuse and Alcoholism (NIAAA)48 enrolled1 locationNCT06269627
Recruiting
Not Applicable

Understanding Pathways to Wellness and Recovery in Detroit - Digital Recovery Support Services

Digital HealthAlcohol Use DisorderRecovery Outcomes
Brandeis University65 enrolled1 locationNCT07724275
Recruiting
Phase 3

A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

Alcohol Use Disorder
Eli Lilly and Company1,100 enrolled120 locationsNCT07219966
Recruiting
Phase 3

A Study of Brenipatide in Participants With Alcohol Use Disorder

Alcohol Use Disorder
Eli Lilly and Company1,100 enrolled117 locationsNCT07219953
Recruiting
Phase 3

Emergency Department-Initiated Medications for Alcohol Use Disorder

Alcohol Use Disorder
Yale University240 enrolled1 locationNCT05827159
Recruiting
Not Applicable

Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment and Reduction of Heavy Drinking in Individuals With of Alcohol Use Disorder (AUD)

AlcoholismAlcohol Use DisorderAlcohol Dependence+3 more
Brainsway186 enrolled9 locationsNCT07216872
Recruiting
Not Applicable

Supporting Adolescent Alcohol Treatment With Computer-Based ('Path180') Skills Training

Alcohol Use Disorder
Brown University112 enrolled1 locationNCT07713251
Recruiting
Phase 1Phase 2

Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease

CirrhosisAlcohol Use DisorderLiver Disease; Alcohol-Related
Virginia Commonwealth University80 enrolled2 locationsNCT05548452
Recruiting
Not Applicable

Wellness, Alcohol, Vitals, and Emotions

Alcohol Use
University of New Mexico120 enrolled1 locationNCT06982443
Recruiting

The Effect of Comorbid Alcohol/Substance Use

SchizophreniaSubstance Use DisordersAlcohol Use Disorder+4 more
Abant Izzet Baysal University297 enrolled1 locationNCT07692984
Recruiting
Phase 2

Study of Tirzepatide for Recovery and Alcohol Use Management

Alcohol Use Disorder (AUD)
Brigham and Women's Hospital20 enrolled2 locationsNCT06727331
Recruiting
Phase 2

Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD

Alcohol Use Disorder
NYU Langone Health200 enrolled1 locationNCT06349083
Recruiting
Phase 1

PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder

Alcohol Use Disorder
National Institute of Mental Health (NIMH)30 enrolled1 locationNCT06795581