RecruitingNot ApplicableNCT06101862

Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary Syndrome

Team-based Interventional Triage in Acute Coronary Syndrome Based on Non-Invasive Computed Tomography Coronary Angiography - a Randomized Trial

Sponsor

Rigshospitalet, Denmark

Enrollment

2,300 participants

Start Date

Oct 1, 2023

Study Type

INTERVENTIONAL

Conditions

Coronary Disease Randomized Controlled Trial Diagnostic Imaging Coronary Artery Disease Ischemic Heart Disease Heart Attack Percutaneous Coronary Intervention Acute Myocardial Infarction (AMI)Non STEMI Angina Pectoris, Unstable Coronary Stenoses Multidetector Computed Tomography

Summary

Coronary computed tomography angiography (CCTA) is a widely accepted initial diagnostic test for individuals suspected of having chronic coronary syndromes. However, there is limited evidence supporting its use in the acute setting. So far, no large-scale randomized trial has examined the performance of CCTA as an alternative to invasive coronary angiography (ICA) in individuals with non-ST-segment elevation myocardial infarction (NSTEACS). If CCTA were to replace ICA as a routine procedure for individuals with NSTEACS, it could reduce the risk of complications related to ICA, improve patient comfort, expedite decision-making, and reduce healthcare expenses and interhospital transfers.

Eligibility

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called CCTA, a procedure called Conventional ICA, and others for people with acute myocardial infarction (ami), angina pectoris, unstable, and other related conditions. The study is currently recruiting participants at 6 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURECCTA

Participants will be examined with CCTA during admission.

PROCEDUREConventional ICA

Patients will be examined with conventional standard-of-care ICA.

OTHERTeam-based interventional triage

The CCTA will be discussed at a coronary CT-team conference to establish the treatment strategy and provide guidance for any necessary interventional procedure.