Coronary Disease Clinical Trials

33 recruiting

Coronary Disease Trials at a Glance

36 actively recruiting trials for coronary disease are listed on ClinicalTrialsFinder across 6 cities in 23 countries. The largest study group is Not Applicable with 16 trials, with the heaviest enrollment activity in Seoul, Seville, and Alicante. Lead sponsors running coronary disease studies include Fundación EPIC, Luzerner Kantonsspital, and Universitätsklinikum Hamburg-Eppendorf.

Browse coronary disease trials by phase

Treatments under study

About Coronary Disease Clinical Trials

Looking for clinical trials for Coronary Disease? There are currently 33 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Coronary Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Coronary Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 36 trials

Recruiting
Not Applicable

Trial of Orbital Atherectomy Versus Standard Strategy in Calcified Bifurcation Lesions

Coronary DiseaseCoronary Artery Disease
Fundación EPIC200 enrolled8 locationsNCT06736899
Recruiting
Not Applicable

Evaluating New Radiation Techniques for Cardiovascular Imaging

Coronary Disease
National Heart, Lung, and Blood Institute (NHLBI)5,000 enrolled1 locationNCT01621594
Recruiting

Restrospective Analysis of MACE in Patients Treated With Drug-elluting Balloons.

Coronary Arterial Disease (CAD)Bifurcation Coronary DiseaseRestenosis, Coronary
Olivier F. Bertrand1,500 enrolled1 locationNCT06972225
Recruiting
Not Applicable

Postprocedural Contrast Mediated FFR Plus Intracoronary Infusion of Nitroglycerin in Multivessel Patients (PROMETEUS TRIAL)

Coronary Disease
Fundación EPIC150 enrolled4 locationsNCT06273293
Recruiting
Not Applicable

Treatment of Functionally Non-significant Vulnerable Plaques in Patients With Multivessel ST-elevation Myocardial Infarction The VULNERABLE Trial

Coronary DiseaseCoronary Artery DiseaseIschemic Heart Disease
Fundación EPIC600 enrolled49 locationsNCT05599061
Recruiting
Not Applicable

Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO IV-EPIC 38)

Arterial Occlusive DiseasesCardiovascular DiseasesCoronary Disease+22 more
Fondazione Ricerca e Innovazione Cardiovascolare ETS576 enrolled1 locationNCT06535568
Recruiting

IRIS- DESyne X2 in the IRIS-DES Registry

Coronary DiseaseCoronary OcclusionCoronary Stenosis
Seung-Jung Park1,000 enrolled6 locationsNCT03588481
Recruiting

Evaluation of Effectiveness and Safety of Synergy XD and Synergy Megatron™ Stent

Cardiovascular DiseasesCoronary DiseaseMyocardial Ischemia+2 more
Jung-min Ahn2,000 enrolled23 locationsNCT05044273
Recruiting

Risk Prediction of Disease Progression in Early-Onset Coronary Atherosclerosis

Coronary DiseaseYoung Adult
Fu Wai Hospital, Beijing, China10,000 enrolled1 locationNCT07316452
Recruiting
Phase 3

One-Month DAPT in CABG Patients

Chronic Coronary Disease
Weill Medical College of Cornell University700 enrolled22 locationsNCT05997693
Recruiting
Not Applicable

SECURE Trial: Stress Echocardiography With Carotid Ultrasound vs Routine CT Coronary Angiography in Chronic Coronary Syndrome for Endpoints

Coronary DiseaseCoronary Artery DiseaseChronic Coronary Syndrome
London North West Healthcare NHS Trust2,000 enrolled1 locationNCT06185530
Recruiting
Phase 4

The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk

Stable Coronary Disease
Brigham and Women's Hospital50 enrolled1 locationNCT05152888
Recruiting
Not Applicable

Long-term Remote Ischemic Preconditioning Improves Myocardial Perfusion and Prognosis of Patients After CABG

Coronary Disease
Henan Institute of Cardiovascular Epidemiology210 enrolled1 locationNCT04779008
Recruiting

Change History and Adopt a Robotic SolutioN for anGioplasty procedurE

Coronary Disease
Robocath500 enrolled8 locationsNCT05853419
Recruiting
Not Applicable

Interventional Strategy for Non-culprit Lesions With Major Vulnerability Criteria at OCT in Patients With ACS

Coronary DiseaseCoronary Artery DiseaseIschemic Heart Disease
Centro per la Lotta Contro l'Infarto - Fondazione Onlus1,420 enrolled34 locationsNCT05027984
Recruiting

The Italian Alliance for Cardiovascular Rehabilitation and Prevention (ITACARE-P) Registry: An Observational Study on Cardiac Rehabilitation in Patients With Coronary Disease or Heart Failure

Heart FailureCoronary DiseaseTelerehabilitation+4 more
Fondazione Don Carlo Gnocchi Onlus1,600 enrolled1 locationNCT07094737
Recruiting
Not Applicable

Digital Implementation of the German S3 Clinical Practice Guideline for Multimorbidity

Heart FailureBreast NeoplasmsObesity+10 more
Universitätsklinikum Hamburg-Eppendorf660 enrolled1 locationNCT06831994
Recruiting

Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures, Third Wave

Heart FailureAsthmaDepressive Disorder+13 more
Universitätsklinikum Hamburg-Eppendorf240 enrolled1 locationNCT06890208
Recruiting
Not Applicable

Myocardial Perfusion Quantification With SPECT Using Multi-Pinhole Collimator Compared to Photon-Counting Coronary CTA

Cardiovascular DiseasesCoronary DiseaseMyocardial Ischemia+6 more
Semmelweis University50 enrolled1 locationNCT06670768
Recruiting

Double Kissing-crush vs Controlled Balloon-crush Techniques For Complex Coronary Bfurcation Lesions

Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)Bifurcation Coronary Disease
Istanbul Mehmet Akif Ersoy Educational and Training Hospital300 enrolled2 locationsNCT06931574