The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma
The Alterations of Brain Network Connectivity Under Sedation and Anesthesia in Patients With Supratentorial Glioma
Beijing Tiantan Hospital
120 participants
Aug 31, 2023
OBSERVATIONAL
Conditions
Summary
Perioperative anesthesia can affect postoperative cognitive function. In our previous study, intraoperative dexmedetomidine (Dex) infusion reduced the incidence of delirium within the first 5 days after brain tumor. However, the mechanism is still unclear. With the development of neuroimaging, multimodal neuroimaging technology provide a new method to explore the underlying mechanism. Therefore, the purpose of this study is to analyze the alterations of brain network under sedation and anesthesia by different anesthetics in patients with supratentorial glioma and their association with cognition.
Eligibility
Plain Language Summary
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Interventions
Participants will be sedated and maintained by dexmedetomidine during the surgery.
Participants will be sedated and maintained by propofol during the surgery.
Participants will be sedated and maintained by remimazolam during the surgery.
Locations(1)
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NCT06138340