SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury

This study is looking at whether a measurement called spleen stiffness (done through an ultrasound-like scan) can predict how severely ill patients with chronic liver disease will become when they have an episode of sudden liver injury (called acute-on-chronic liver failure). **You may be eligible if...** - You are between 18 and 80 years old - You have chronic liver disease (from any cause) - You are currently in the hospital with an acute liver injury, shown by a bilirubin level of 3 mg/dL or higher **You may NOT be eligible if...** - You have had liver transplant, a liver shunt procedure (TIPS), or spleen surgery before - You have advanced kidney failure, severe COPD, or had a heart attack within 3 months - You have been diagnosed with liver cancer or another active cancer - You are pregnant - Your jaundice (yellowing of the skin) is caused by a blocked bile duct Talk to your doctor to see if this trial is right for you.