RecruitingNot ApplicableNCT06212700

PRIORITY-CONNECT 2 Pilot Trial

Virtual Multimodal Hub for Patients Undergoing Major Gastrointestinal Cancer Surgery - PRIORITY-CONNECT 2 Pilot Randomised Type I Hybrid Effectiveness-Implementation Trial


Sponsor

Surgical Outcomes Research Centre (SOuRCe)

Enrollment

20 participants

Start Date

Feb 12, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The provision of preoperative interventions (prehabilitation: including exercise, nutrition, and psychological treatment) have been reported to reduce postoperative complications by as much as 50% and reduce hospital stay by up to 4 days compared to standard of care. Postoperative multimodal interventions are likely to further benefit patients facing new challenges (e.g. stoma care), and reduce post discharge complications. Therefore the Virtual Multimodal hub of PRIORITY-CONNECT 2 Pilot Trial aims to primarily; determine the feasibility of incorporating a virtual multimodal program into the preoperative and postoperative period for patients undergoing gastrointestinal cancer surgery, the acceptability to patients, clinicians and carers of the virtual multimodal program and the acceptability to patients of being randomised to the virtual multimodal program or usual care. The secondary aim is to obtain pilot data on the likely difference in key outcomes (30 days postoperative complications, quality of life, days at home and alive at 30 days - DAH30, implementation outcomes and cost outcomes) to inform the development of a substantive randomised clinical trial.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Adults aged ≥18 years undergoing major gastrointestinal elective surgery, including liver, pancreas, oesophagus, gastric and colorectal cancer resections with curative intent
  • Consulting with a gastrointestinal cancer surgeon at least 1 week prior to scheduled surgery

Exclusion Criteria2

  • Cognitive impairment such that they are unable to provide informed consent
  • No access to a smart device (including mobile phone, tablet, laptop or desk computer with camera) or no internet connection

Interventions

BEHAVIORALPreoperative Exercise

Aerobic (HIIT) Endurance Respiratory Muscle Strength Education

BEHAVIORALPostoperative Exercise

Aerobic Muscle Strength Walking Program Education

DIETARY_SUPPLEMENTPreoperative Nutrition

Malnutrition screening Weight monitoring Symptom management Dietetic counselling Nutrition support

DIETARY_SUPPLEMENTPostoperative Nutrition

Malnutrition screening Weight monitoring Symptom management Dietetic counselling Nutrition support

BEHAVIORALPreoperative Psychology

CBT skills Skills training Emotional validation Behavioural activation Psycho-education

BEHAVIORALPostoperative Psychology

CBT skills Skills training Emotional validation Behavioural activation Psycho-education

OTHERPreoperative Nursing

Comorbidities Managing pain Wound care Complications Surgical education ERAS

OTHERPostoperative Nursing

Managing pain Cardiovascular stability Wound care Bowel function/Stoma Complications Education

OTHERPreoperative Peer Support Group

Weekly sessions moderated by a social worker including patients and carers: Safe space Share experiences/ideas Support Education

OTHERPostoperative Peer Support Group

Weekly sessions moderated by a social worker including patients and carers: Safe space Share experiences/ideas Support Education

OTHERUsual Care

Participants allocated to the control group will receive usual care according to their health care team, which may consist of advice on smoking cessation, reduction of alcohol intake, nutritional counselling, and medical optimisation in the preoperative anaesthetic clinic visits.


Locations(2)

Chris O'Brien Lifehouse

Sydney, New South Wales, Australia

Royal Prince Alfred Hospital, Surgical Outcomes Research Centre (SOuRCe)

Sydney, New South Wales, Australia

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NCT06212700


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