RecruitingNCT06234410

Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation


Sponsor

University of Edinburgh

Enrollment

332 participants

Start Date

Jan 24, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Cardiovascular disease (for example, heart attack, stroke, heart failure) is the commonest complication of kidney failure. Kidney transplantation reduces cardiovascular risk but cardiovascular disease remains the commonest cause of death in patients following transplantation. Current strategies to assess patient's cardiovascular risk prior to kidney transplantation do not identify those at highest risk and do not improve outcomes. This study will use a heart scan known as computed tomography coronary angiography (CTCA) to see whether this scan can identify patients at highest risk of future cardiovascular disease prior to transplantation. Studies have shown it is able to do this in patients with normal kidney function. The aim of this study is to develop CTCA as an effective tool to risk stratify patients prior to kidney transplantation.


Eligibility

Min Age: 16 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a CT coronary angiography scan (a detailed X-ray of heart arteries) is useful for assessing heart disease risk in patients who are waiting for a kidney transplant. **You may be eligible if...** - You have kidney failure and are on the waiting list for a kidney transplant - You are 16 years or older - You are able to give consent to participate **You may NOT be eligible if...** - You cannot have a CT scan (for example, due to a dye/contrast allergy) - You are being considered for a combined transplant (kidney plus pancreas, liver, or islet cells) - You are not able to give informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONComputed tomography coronary angiography (CTCA)

Single CTCA scan prior to kidney transplantation


Locations(2)

Royal Infirmary of Edinburgh

Edinburgh, Lothian, United Kingdom

Queen Elizabeth Hospital

Glasgow, United Kingdom

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NCT06234410


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