A Study of the Association Between Frailty and Acute Postoperative Pain in Elderly Thoracoscopic Surgery Patients
A Study on the Association Between Frailty and Acute Postoperative Pain in Elderly Patients Undergoing Thoracoscopic Surgery and an Investigation of the Mechanisms Involved
Huazhong University of Science and Technology
78 participants
Mar 12, 2024
OBSERVATIONAL
Conditions
Summary
To gain a clearer understanding of the association between frailty and postoperative acute pain in elderly thoracoscopic surgery patients and its underlying mechanisms, to provide new solution ideas to reduce the level of postoperative acute pain and improve the debilitating state of elderly thoracoscopic surgery patients, and consequently improve their quality of life and mental status.
Eligibility
Inclusion Criteria5
- patients undergoing thoracic surgery under general anesthesia with 48 h of postoperative patient-controlled analgesia;
- age ≥60 years;
- ASA class I-III;
- signed informed consent;
- patients undergoing thoracoscopic surgery.
Exclusion Criteria8
- Patients who themselves refuse to participate in the study;
- Drug dependence;
- Patients who cannot cooperate with communication and have verbal communication difficulties;
- Patients who cannot assess frailty preoperatively and pain postoperatively;
- Failure to provide a compliant fecal sample at the agreed time;
- antibiotic treatment within the last month;
- intestinal dysfunction (e.g., irritable bowel syndrome, inflammatory bowel disease, chronic diarrhea, and other types of intestinal disorders);
- comorbidities of certain metabolic disorders (e.g., thyroid dysfunction, diabetes mellitus, and so on) that may affect the structure of the microbial community;
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Locations(1)
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NCT06281275