acute postoperative pain Clinical Trials

12 recruitingLast updated: May 9, 2026

There are 12 actively recruiting acute postoperative pain clinical trials across 8 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3. Top locations include Amiens, France, Cairo, Egypt, Changsha, Hunan, China. Updated daily from ClinicalTrials.gov.


acute postoperative pain Trials at a Glance

12 actively recruiting trials for acute postoperative pain are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Amiens, Cairo, and Changsha. Lead sponsors running acute postoperative pain studies include Shanghai Yidian Pharmaceutical Technology Development Co., Ltd., Centre Hospitalier Universitaire, Amiens, and Cairo University.

Browse acute postoperative pain trials by phase

Treatments under study

About acute postoperative pain Clinical Trials

Looking for clinical trials for acute postoperative pain? There are currently 12 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new acute postoperative pain trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about acute postoperative pain clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Not Applicable

Intertransverse Process Block for Postoperative Analgesia After Thoracotomy and Lobectomy

Thoracotomy surgeryacute postoperative painIntertransverse Process Block
Konya City Hospital66 enrolled1 locationNCT07335250
Recruiting
Not Applicable

DIPB vs. SIFIB for Postoperative Analgesia After Hip Surgery

Hip Arthroplastyacute postoperative painPostoperative Pain+1 more
Sivas Numune Hospital70 enrolled2 locationsNCT07452120
Recruiting
Phase 2

Evaluate the Safety and Efficacy of HL-1186 Tablet for Postoperative Pain Management in Abdominal Surgery

Moderate to Severe Acute Postoperative Pain
Shanghai Yidian Pharmaceutical Technology Development Co., Ltd.40 enrolled1 locationNCT07311369
Recruiting
Phase 2

Evaluate the Safety and Efficacy of HL-1186 Tablet for Moderate to Severe Acute Pain After Surgery

Moderate to Severe Acute Postoperative Pain
Shanghai Yidian Pharmaceutical Technology Development Co., Ltd.72 enrolled1 locationNCT07147049
Recruiting

Nudging to Promote the Use of Transcutaneous Electrical Nerve Stimulation for Postoperative Pain Relief

Acute Postoperative Pain in Urological SurgeryPain Management in Postoperative Care (Including Opioid-Sparing Approaches)
Pether Jildenstal500 enrolled5 locationsNCT06696430
Recruiting
Phase 3

Non-steroidal Anti-inflammatory in Cardiac Surgery

Pain intensityacute postoperative painCardiac Surgery+2 more
Centre Hospitalier Universitaire, Amiens238 enrolled1 locationNCT06381063
Recruiting
Phase 4

Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty

acute postoperative painSurgery
University of California, San Diego40 enrolled1 locationNCT06784882
Recruiting

Clinical Prediction of Post-surgical Pain

acute postoperative painChronic post operative pain
Aarhus University Hospital748 enrolled2 locationsNCT06661642
Recruiting
Not Applicable

Cryoneurolysis for Acute Postoperative Pain Following Total Knee Arthroplasty

acute postoperative pain
Copenhagen University Hospital, Hvidovre44 enrolled1 locationNCT06088602
Recruiting

A Study of the Association Between Frailty and Acute Postoperative Pain in Elderly Thoracoscopic Surgery Patients

acute postoperative painFrailty
Huazhong University of Science and Technology78 enrolled1 locationNCT06281275
Recruiting
Phase 4

Bupivacaine 0.125% Versus Bupivacaine 0.25% in Superficial Cervical Plexus Block for Tympanomastoid Surgeries in Adults

acute postoperative painSurgical Field
Cairo University60 enrolled1 locationNCT06381401
Recruiting

The relationship between the numeric rating scale, as a subjective measure of postoperative pain, and the plasma levels of catecholamines

acute postoperative pain
Thomas Ledowski85 enrolled1 locationACTRN12610000454077