RecruitingNot ApplicableNCT06310161

Light Therapy in End Stage Kidney Disease

Bright Light Therapy to Treat Fatigue in End Stage Kidney Disease


Sponsor

University of Pennsylvania

Enrollment

60 participants

Start Date

Feb 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to test light therapy in patients with end stage kidney disease who are receiving hemodialysis. The main aim is to determine if light therapy decreases fatigue severity. Participants will receive light therapy using special glasses for one hour during the dialysis sessions for four weeks of treatment.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether light therapy (exposure to a bright light device) can reduce fatigue in patients with end-stage kidney disease who are on regular hemodialysis (kidney dialysis three times per week). Fatigue is one of the most common and disabling symptoms in dialysis patients, and light therapy may help by resetting the body clock and improving sleep. **You may be eligible if...** - You are 18 years or older - You have end-stage kidney disease and have been receiving hemodialysis three times per week for at least one month - You experience significant fatigue (score above 9 on the Fatigue Severity Scale) - You have a home refrigerator (needed to store saliva samples for the study) **You may NOT be eligible if...** - You have eye conditions such as cataracts, glaucoma, or macular degeneration - You have a condition that makes you sensitive to light, such as photosensitive epilepsy - You are currently hospitalized or acutely ill Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEBright light

Bright light treatment will consist of using the Re-timer device 3 times per week during dialysis sessions for 4 weeks. The Re-timer is worn like a pair of glasses and contains light emitting diodes mounted on the lower portion of the frame. The Re-timer emits blue-green 500 nm light with an intensity of \~500 lux lm/m2. Participants will be instructed to use the device for 60 minutes at the beginning of each dialysis session.

DEVICEDim Light

Dim light treatment will use non-light emitting glasses that look identical to Re-Timer for 4 weeks at each dialysis session following baseline assessments. Participants will use the device for 60 minutes at the beginning of their dialysis session.


Locations(1)

University of Pennsylvania

Philadelphia, Pennsylvania, United States

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NCT06310161


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