Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite Polypharmacy

This study is evaluating a minimally invasive surgical procedure called MIMS (Minimally Invasive Micro Sclerostomy) for lowering eye pressure in patients with open-angle glaucoma that remains uncontrolled despite using multiple eye drops. The device creates a tiny drainage channel in the eye to allow fluid to escape and reduce pressure. **You may be eligible if...** - You are between 40 and 85 years old - You have open-angle glaucoma with elevated eye pressure (21–40 mmHg) even while using multiple prescription eye drops - Your glaucoma has caused measurable visual field loss and structural damage to the optic nerve - The white part of your eye (conjunctiva) in the target area is healthy and free of scarring - Any previous minimally invasive glaucoma procedures were done more than 6 months ago **You may NOT be eligible if...** - Your eye pressure is above 40 mmHg or is controlled on medications - You have scarring or damage to the conjunctiva in the target area - You have had a prior surgery that would prevent the MIMS procedure (such as a trabeculectomy or tube shunt) - You have active eye inflammation or other eye conditions that could affect results Talk to your doctor to see if this trial is right for you.