RecruitingNCT06316895

The Clinical Outcomes and Prediction of Thermal Ablation for Low-risk Papillary Thyroid Carcinoma

The Clinical Outcomes and Artificial Intelligence Prediction Model of Ultrasound-guided Thermal Ablation for the Treatment of Low-risk Papillary Thyroid Carcinoma

Sponsor

Chinese PLA General Hospital

Enrollment

3,772 participants

Start Date

Apr 1, 2024

Study Type

OBSERVATIONAL

Conditions

Papillary Thyroid Cancer

Summary

1. To evaluate the clinical outcomes of ultrasound-guided thermal ablation and thyroid surgery for the treatment of papillary thyroid carcinoma; 2. To develop and validate a artificial intelligence model to predict the outcomes of ultrasound-guided thermal ablation in the treatment of papillary thyroid carcinoma;

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria5

patients age between 18 and 80 year old, both sex
papillary thyroid carcinoma confirmed by core-needle biopsy or fine-needle aspiration
the largest diameter ≤2.0 cm
no clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on ultrasound, nech and chest CT
follow-up period ≥12 months,

Exclusion Criteria6

patients with convincing evidence of aggressive papillary thyroid carcinoma or other type of thyroid cancer by biopsy
history of neck radiation
history of thyroid surgery
coagulation disorder
serious heart, respiratory, liver, or renal failure
dysfunction of the vocal cord on the opposite side