RecruitingNot ApplicableNCT06318715

Modified Deep Extubation vs. Standard Awake Extubation

A Comparison of a Modified Deep Extubation to Standard Awake Extubation for Decreasing Operating Room Time: a Randomized Controlled Trial


Sponsor

Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Enrollment

60 participants

Start Date

Apr 8, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The proposed study is to compare a modified DE technique, which is regularly used for low-risk patients by staff anesthesiologists at our institution, to a standard awake extubation. This modified deep extubation (mDE) occurs while the patient is still anaesthetized but at a lower dose of anaesthetic gas than previously described, and balanced with long acting opioids to attenuate the airway reaction. As previously stated, the literature shows that the risks of DE are equivalent to those of regular AE practice. Our hypothesis is that mDE will shorten the time from the end of the surgery (completion of last stitch) to the moment the patient is ready to leave the OR by at least 5 minutes when compared to standard AE practice.


Eligibility

Inclusion Criteria2

  • ASA I-III
  • laparoscopic surgery under general anesthesia

Exclusion Criteria11

  • High-risk patients:
  • Documented difficult airway during intubation or developed intraoperatively.
  • Full stomach
  • Pregnant women
  • Emergency surgery
  • BMI>30
  • Intraoperative bleeding leading to transfusion
  • Use of remifentanil during extubation
  • Requirement for prone position for surgical approach (i.e., spine surgery, anal fistulectomy, tumor resection of the back, etc)
  • Absolute indication for awake or deep extubation
  • Use of opioids in chronic pain patients

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Interventions

PROCEDUREmodified deep extubation (mDE)

The proposed study is to compare a modified DE technique, which is regularly used for low-risk patients by staff anesthesiologists at our institution, to a standard awake extubation.

PROCEDUREstandard awake extubation

awake extubation (AE) is still considered the standard practice.


Locations(1)

Department of Anesthesia Mount Sinai Hospital

Toronto, Ontario, Canada

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NCT06318715


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