RecruitingNot ApplicableNCT06335914

Dual PSMA and FDG PET Imaging for Patients With Advanced Prostate Cancer


Sponsor

University Health Network, Toronto

Enrollment

30 participants

Start Date

Apr 3, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study will use Prostate Specific Membrane Antigen (PSMA) and (18)F-Fluorodeoxyglucose Positron Emission Tomography (FDG PET) imaging in patients with advanced prostate cancer to learn about tumor biology across disease stages and during treatment. This may help with treatment selection and potential response monitoring in the future.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is using two types of PET scans — a standard FDG scan and a newer PSMA scan — to monitor how well treatment is working in men with advanced, metastatic prostate cancer. Using both scans together may give a more complete picture of how the cancer is responding. **You may be eligible if...** - You are a male aged 18 or older - You have been diagnosed with metastatic castration-sensitive prostate cancer (mCSPC) — meaning the cancer has spread but still responds to testosterone-blocking therapy - You are starting or have recently started androgen-deprivation therapy (ADT) with a hormone-blocking drug - You are receiving care at Princess Margaret Cancer Centre **You may NOT be eligible if...** - You are enrolled in a randomized clinical trial with restrictions on additional imaging - You have had a PSMA or FDG PET scan within the last 60 days at a required study time point Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DIAGNOSTIC_TESTGa 68 PSMA-11 PET

Positron emission tomography (PET) imaging using Ga68 PSMA 11 radiotracer

DIAGNOSTIC_TEST18F-DCFPyL PET

Positron emission tomography (PET) imaging using 18F-DCFPyL radiotracer.

DIAGNOSTIC_TESTFDG PET

Positron emission tomography (PET) imaging using (18) F-fluorodeoxyglucose radiotracer.


Locations(1)

Princess Margaret Cancer Centre

Toronto, Ontario, Canada

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06335914


Related Trials