Advanced Prostate Cancer Clinical Trials

15 recruiting

Advanced Prostate Cancer Trials at a Glance

21 actively recruiting trials for advanced prostate cancer are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Phase 1 with 9 trials, with the heaviest enrollment activity in Shanghai, Lyon, and Barcelona. Lead sponsors running advanced prostate cancer studies include Jiangsu HengRui Medicine Co., Ltd., Brigham and Women's Hospital, and Angela Y. Jia, MD PhD.

Browse advanced prostate cancer trials by phase

Treatments under study

About Advanced Prostate Cancer Clinical Trials

Looking for clinical trials for Advanced Prostate Cancer? There are currently 15 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Advanced Prostate Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Advanced Prostate Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 21 trials

Recruiting

Lab Research Using Mini-tumors to Study Prostate Cancer Treatments

Prostate CancerAdvanced Prostate CancerProstate Cancer Metastatic Disease+1 more
Maastricht Radiation Oncology600 enrolled3 locationsNCT07004582
Recruiting
Phase 1

A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer

Advanced Prostate CancerMetastatic Prostate Cancer
Genentech, Inc.210 enrolled25 locationsNCT05800665
Recruiting
Phase 2Phase 3

PRO-BOOST-N: Prostate-First Versus Combined Prostate and Nodal Dose Escalation in PSMA PET-Staged Node-Positive Prostate Cancer

Prostate CancerBrachytherapyStereotactic Body Radiation Therapy (SBRT)+2 more
Affidea Nu-med Center of Oncological DIagnostics and Therapy1,600 enrolled1 locationNCT07426094
Recruiting
Not Applicable

Engage Psychosocial Intervention for Cancer Symptoms

Advanced Breast CancerAdvanced Prostate CancerAdvanced Lung Cancer+2 more
Duke University190 enrolled1 locationNCT06555588
Recruiting
Phase 1

PRORAD-5 PROstate RADiation in 5 Fractions: Phase II Five Fraction Radiotherapy for Patients With Advanced Prostate Cancer.

Advanced Prostate Cancer
M.D. Anderson Cancer Center70 enrolled1 locationNCT06369246
Recruiting
Phase 1

Relugolix + Enzalutamide Study in High-Risk Prostate Cancer

Androgen Deprivation TherapyLocally Advanced Prostate Cancer
University of Oklahoma46 enrolled1 locationNCT06130995
Recruiting
Phase 1

A Study of JNJ-87189401 Plus JNJ-78278343 for Advanced Prostate Cancer

Advanced Prostate Cancer
Janssen Research & Development, LLC250 enrolled6 locationsNCT06095089
Recruiting
Not Applicable

Dual PSMA and FDG PET Imaging for Patients With Advanced Prostate Cancer

Advanced Prostate Cancer
University Health Network, Toronto30 enrolled1 locationNCT06335914
Recruiting
Not Applicable

Addition of Focal Boost to Primary Radiotherapy for Prostate Cancer in 12 or 20 Fractions

Locally Advanced Prostate CancerProstate Cancer Patients Undergoing External Radiation and Seed ImplantationHigh Risk Localised Prostate Carcinoma+1 more
Rigshospitalet, Denmark1,016 enrolled3 locationsNCT07343349
Recruiting
Phase 1

Phase Ib Study of HS-20093+HRS-5041 in Patients With Advanced Prostate Cancer

Advanced Prostate Cancer
Hansoh BioMedical R&D Company63 enrolled1 locationNCT07115446
Recruiting
Phase 1Phase 2

STereotActic Body Radiotherapy and 177Lutetium PSMA in Locally Advanced Prostate Cancer

Malignant Neoplasm of ProstateLocally Advanced Prostate Cancer
Angela Y. Jia, MD PhD45 enrolled1 locationNCT06574880
Recruiting
Phase 1

Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT

Advanced Prostate CancerMetastatic Prostate CancerMetastatic Prostate Neuroendocrine Carcinoma
Brigham and Women's Hospital30 enrolled2 locationsNCT06062745
Recruiting
Phase 1

HS-10502 Combination Treatment in Patients With Advanced Solid Tumors

Advanced Breast CancerAdvanced Prostate CancerTNBC+3 more
Jiangsu Hansoh Pharmaceutical Co., Ltd.157 enrolled1 locationNCT06769425
Recruiting
Not Applicable

Improved Robotic-Assisted Radical Prostatectomy for Locally Advanced Prostate Cancer: Bladder Suspension and Preliminary Outcomes

Locally Advanced Prostate CancerRobotic-Assisted Radical ProstatectomyBladder Suspension
First Affiliated Hospital of Fujian Medical University300 enrolled1 locationNCT06977906
Recruiting

Whole Body MRI in Oncology

Advanced Breast CancerAdvanced Prostate CancerMultiple Myeloma+3 more
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS1,000 enrolled3 locationsNCT06895291
Recruiting

European Registry of Next Generation Imaging in Advanced Prostate Cancer

Prostate CancerAdvanced Prostate CancerMetastatic Prostate Cancer (mPC)
Fundacio Puigvert600 enrolled24 locationsNCT06866782
Recruiting
Phase 1

Study of HRS-5041 in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

Advanced Prostate Cancer
Jiangsu HengRui Medicine Co., Ltd.100 enrolled1 locationNCT05942001
Recruiting
Phase 3

Efficacy and Safety of DKF-MA102 in Patients With Prostate Cancer

Advanced Prostate Cancer
Dongkook Pharmaceutical Co., Ltd.154 enrolled1 locationNCT06490328
Recruiting
Phase 2

Genomic Biomarker-guided Neoadjuvant Therapy for Prostate Cancer (SEGNO)

Locally Advanced Prostate CancerOligometastatic Prostate Cancer
The First Affiliated Hospital of Xiamen University40 enrolled1 locationNCT06387056
Recruiting
Phase 3

A Trial of SHR3680 in Prostate Cancer Patients Who Are Candidates for Radical Prostatectomy

Patients With High-risk Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy
Jiangsu HengRui Medicine Co., Ltd.1,256 enrolled1 locationNCT05009290